Predicting visual acuity with machine learning in treated ocular trauma patients  

作　　者：Zhi-Lu Zhou Yi-Fei Yan Jie-Min Chen Rui-Jue Liu Xiao-Ying Yu Meng Wang Hong-Xia Hao Dong-Mei Liu Qi Zhang Jie Wang Wen-Tao Xia 

机构地区：[1]Department of Forensic Medicine,Guizhou Medical University,Guiyang 550009,Guizhou Province,China [2]Shanghai Key Laboratory of Forensic Medicine,Shanghai Forensic Service Platform,Institute of Forensic Science,Ministry of Justice,Shanghai 200063,China [3]The SMART(Smart Medicine and AI-based Radiology Technology)Lab,Shanghai Institute for Advanced Communication and Data Science,Shanghai University,Shanghai 200444,China [4]School of Communication and Information Engineering,Shanghai University,Shanghai 200444,China [5]Basic Medical College,Jiamusi University,Jiamusi 154007,Heilongjiang Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2023年第7期1005-1014,共10页国际眼科杂志（英文版）

基　　金：Supported by National Key R&D Program of China(No.2022YFC3302001);the Human Injury and Disability Degree Classification(No.SF20181312);the National Natural Science Foundation of China(No.62071285)。

摘　　要：AIM:To predict best-corrected visual acuity(BCVA)by machine learning in patients with ocular trauma who were treated for at least 6mo.METHODS:The internal dataset consisted of 850 patients with 1589 eyes and an average age of 44.29y.The initial visual acuity was 0.99 log MAR.The test dataset consisted of 60 patients with 100 eyes collected while the model was optimized.Four different machine-learning algorithms(Extreme Gradient Boosting,support vector regression,Bayesian ridge,and random forest regressor)were used to predict BCVA,and four algorithms(Extreme Gradient Boosting,support vector machine,logistic regression,and random forest classifier)were used to classify BCVA in patients with ocular trauma after treatment for 6mo or longer.Clinical features were obtained from outpatient records,and ocular parameters were extracted from optical coherence tomography images and fundus photographs.These features were put into different machine-learning models,and the obtained predicted values were compared with the actual BCVA values.The best-performing model and the best variable selected were further evaluated in the test dataset.RESULTS:There was a significant correlation between the predicted and actual values[all Pearson correlation coefficient(PCC)>0.6].Considering only the data from the traumatic group(group A)into account,the lowest mean absolute error(MAE)and root mean square error(RMSE)were 0.30 and 0.40 log MAR,respectively.In the traumatic and healthy groups(group B),the lowest MAE and RMSE were 0.20 and 0.33 log MAR,respectively.The sensitivity was always higher than the specificity in group A,in contrast to the results in group B.The classification accuracy and precision were above 0.80 in both groups.The MAE,RMSE,and PCC of the test dataset were 0.20,0.29,and 0.96,respectively.The sensitivity,precision,specificity,and accuracy of the test dataset were 0.83,0.92,0.95,and 0.90,respectively.CONCLUSION:Predicting BCVA using machine-learning models in patients with treated ocular trauma is accurate and helpful

关 键 词：ocular trauma predicting visiual acuity best-corrected visual acuity visual dysfunction machine learning 

分 类 号：TP181[自动化与计算机技术—控制理论与控制工程] R779.1[自动化与计算机技术—控制科学与工程]