脱细胞真皮联合刃厚皮修复儿童皮肤软组织缺损创面的临床效果  

Clinical Effect of Human Acellular Dermal Matrix Combined with Split-thickness Skin on Repairing Skin and Soft Tissue Defect in Children

作　　者：韩志新 牛大伟 樊昌伟 李振超[1] HAN Zhixin;NIU Dawei;FAN Changwei;LI Zhenchao(Department of Burn and Plastic Surgery,People's Hospital of Anyang City,Anyang 455000,Henan,China)

机构地区：[1]安阳市人民医院整形烧伤科,河南安阳455000

出　　处：《中国美容医学》2023年第7期5-8,共4页Chinese Journal of Aesthetic Medicine

基　　金：河南省医学科技攻关计划联合共建项目(编号:LHGJ20191274);安阳市科技攻关项目(编号:2021C01SF047)。

摘　　要：目的:探讨脱细胞真皮联合刃厚皮修复儿童皮肤软组织缺损的临床效果和可行性。方法:回顾性分析2017年2月-2021年2月笔者医院收治的60例皮肤软组织缺损患儿临床资料,根据不同手术方案分为观察组(n=30)和对照组(n=30),观察组采用脱细胞真皮(Human acellular dermal matrix,HADM)+刃厚皮片修复创面,对照组采用中厚皮片修复创面。术后10 d,计算皮片成活率;观察记录术后创面愈合时间、术后换药次数,检测术后创面分泌物细菌培养阳性率;术后6个月,采用温哥华瘢痕量表(Vancouver scar scale,VSS)评估患儿瘢痕。结果:术后,观察组移植皮片成活率高于对照组,创面愈合时间短于对照组,换药次数少于对照组,分泌物阳性结果低于对照组,VSS评分低于对照组,差异均有统计学意义(P<0.05)。结论:脱细胞真皮联合刃厚皮修复儿童皮肤缺损创面临床疗效好,瘢痕轻,值得临床推广。Objective To explore the clinical effect and feasibility of allogenic acellular dermal matrixon combined with split-thickness skin on repairing children's skin defects.Methods Clinical data of 60 children with skin and soft tissue defects admitted to the author's hospital from February 2017 to February 2021 were retrospectively analyzed.and were divided into observation group(n=30)and control group(n=30)according to different surgical protocols.Human acellular dermal matrix(HADM)+thick blade skin was used to repair the wound in the observation group,and medium and thick skin was used in the control group.The survival rate of the skin was calculated 10 days after operation.Postoperative wound healing time and dressing change times were observed and the positive rate of bacterial culture in wound secretions was detected.The vancouver scar scale(VSS)was used to evaluate scars 6 months after surgery.Results After surgery,the survival rate of skin grafts in observation group was higher than that in control group,the wound healing time was shorter,the dressing times were less than that in control group,the positive results of secretions were lower than that in control group,and the VSS score was lower,with statistical signifi cance(P<0.05).Conclusion Acellular dermis combined with sharp edge thick skin to repair children's skin defect wound has good clinical effect and light scar,which is worthy of clinical promotion.

关 键 词：皮肤软组织缺损 脱细胞真皮 刃厚皮 修复 临床效果 

分 类 号：R622[医药卫生—整形外科]