三重四极杆液相色谱质谱法测定工作场所空气中β-萘胺  

Determination ofβ-naphthylamine in workplace air by mass spectrometry with triple quadrupole liquid chromatography

作　　者：岳小春 邱景富[1] 杨伟[2] 戴锐睿[2] 杨乾展[3] YUE Xiaochun;QIU Jingfu;YANG Wei;DAI Ruirui;YANG Qianzhan(College of Public Health,Chongqing Medical University,Chongqing,400016,China;Chongqing Center for Disease Control and Prevention,Chongqing,400042,China;Shimadzu Enterprise Management(China)Co.,Ltd.Chongqing Branch,Chongqing,400010,China)

机构地区：[1]重庆医科大学公共卫生学院,重庆400016 [2]重庆市疾病预防控制中心,重庆400042 [3]岛津企业管理(中国)有限公司重庆分公司,重庆400010

出　　处：《环境化学》2023年第7期2492-2495,共4页Environmental Chemistry

基　　金：重庆市2022年科卫联合医学科研项目(2022MSXM099)资助.

摘　　要：本文建立了工作场所空气中β-萘胺的检测方法,采用高分辨液相色谱质谱仪,通过优化采样方法和检测条件,检测工作场所空气中β-萘胺.结果表明,萘胺的两个异构体在本文的实验条件下可以实现完全分离,精确定性.本方法对β-萘胺萘胺的检出限为5.6×10^(−2)μg·L^(−1),线性范围为1.00—100.00μg·L^(−1);10.00、50.00、100.00μg·L^(−1)样品加标回收率范围为92.1%—97.2%,定量重复性为3.20%—5.18%.本检测方法可用于工作场所空气中痕量β-萘胺的定性定量分析.To establish the method for determination ofβ-naphthylamine in workplace air by ultra performance liquid chromatography with high resolution mass spectrometry under optimized sampling method and detection parameters.The results indicated that the two isomers of naphthylamine could be completely separated and accurately characterized using the experimental conditions in this paper.The limits of detection ofβ-naphthylamine were 5.6×10^(-2)μg·L−1,the linear ranges were 1.00—100.00μg·L^(−1);The recoveries of 10.00,50.00 and 100.00μg·L−1 were 92.1%—97.2%,and the quantitative reproducibilities were 3.20%—5.18%.This promising method can be used for the qualitative and quantitative analysis of traceβ-naphthylamine in workplace air.

关 键 词：工作场所空气 β-萘胺. 

分 类 号：O657.63[理学—分析化学] R134.4[理学—化学]