奕韵本草饮辅助改善卵巢功能临床研究  

Clinical Study on Yiyun Materia Medica Yin in Auxiliary Improving Ovarian Function

作　　者：寇秋爱[1] 夏立营[1] 王文乾 杨家熙 孙文婷 张颖 袁景泉 杨宜婷 KOU Qiu-ai;XIA Li-ying;WANG Wen qian;YANG Jia-xi;SUN Wen-ting;Zhang Ying;YUAN Jing-quan;YANG Yi-ting(Health Care Research Center of Traditional Chinese Medicine,Xiyuan Hospital,Chinese Academy of Chinese Medical Sciences,Beijing,100091,China;Clinical School of Medicine,Beijing University of Chinese Medicine,Beijing,100029,China;Infi nitus(China)Co.,LTD,Guangzhou Guangdong,510405,China)

机构地区：[1]中国中医科学院西苑医院中医药保健研究中心,北京100091 [2]北京中医药大学临床医学院,北京100029 [3]无限极(中国)有限公司,广东广州510405

出　　处：《中华养生保健》2023年第16期1-4,共4页CHINESE HEALTH CARE

摘　　要：目的评价奕韵本草饮对卵巢储备功能的辅助改善作用,为治疗卵巢储备功能减退提供新途径。方法选取2020年8月—2021年4月中国中医科学院西苑医院招募的64例卵巢储备功能减退者作为研究对象,根据入组顺序将受试者分为试验组与对照组,每组32例,观察周期均为12周,比较两组受试者试食前后性激素水平、双侧窦卵泡数(AFC)、抗缪勒管激素(AMH)、性生活指标、月经指标以及症状体征积分的变化。结果试食前,两组受试者FSH、AFC、AMH、性生活指标、月经指标及症状体征积分比较,差异无统计学意义(P>0.05),均衡性良好;试食后,试验组FSH较前减低,AFC、AMH及性生活指标、症状体征积分均较试食前有所改善,其中试验组试食后FSH、性生活指标及症状体征积分较对照组改善明显,差异有统计学意义(P<0.05)。结论奕韵本草饮对卵巢储备功能减退有一定的辅助改善作用,而且安全性良好。Objective To evaluate the auxiliary eff ect of Yiyun Materia Medica Yin in improving the ovarian reserve,so as to provide a way for early treatment of DOR.Methods A total of 64 subjects with diminished ovarian reserve who were recruited were enrolled in this study from August 2020 to April 2021.They were assigned to two groups:the experimental group and the control group,according to the sequence,with 32 cases in each group.The trail continued twelve weeks.After the trail,the sex hormone levels,number of bilateral sinus follicles,sexual life indicators,menstrual indicators and symptom and sign scores of the two groups of subjects were compared between the two groups before and after treatment.Result Before the trail,there was no signifi cant diff erence in all indicators between the two groups(P>0.05).After the trail,the FSH in the experimental group was lower than before,and the scores of AFC,AMH,sexual life indicators,symptoms and signs were improved compared with at the begining of the trail.The FSH,sexual life indicators,symptoms and signs were signifi cantly diff erent from those in the control group after the trail(P<0.05).Conclusion Yiyun Materia Medica Yin can eff ectively improve the decreased ovarian reserve,and the safety is good.

关 键 词：卵巢储备功能下降 奕韵本草饮 临床研究 

分 类 号：R271[医药卫生—中医妇科学]