中国40~65岁女性围绝经期综合征发生率的Meta分析  

Incidence of Perimenopausal Syndrome in Chinese Women Aged 40 to 65 Years:a Meta-analysis

作　　者：贾钰 周紫彤 曹学华[2] 胡婉琴 向凤 熊浪宇 王晓霞 JIA Yu;ZHOU Zitong;CAO Xuehua;HU Wanqin;XIANG Feng;XIONG Langyu;WANG Xiaoxia(School of Nursing,Chengdu University of Traditional Chinese Medicine,Chengdu 610036,China;Department of Obstetrics and Gynecology,Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital,Chengdu 610027,China)

机构地区：[1]成都中医药大学护理学院,四川省成都市610036 [2]四川省医学科学院、四川省人民医院妇产科,四川省成都市610027

出　　处：《中国全科医学》2023年第32期4080-4088,共9页Chinese General Practice

摘　　要：背景随着我国经济社会的飞速发展,居民生活水平和自我健康保健意识显著提升,我国人口平均预期寿命逐渐延长,围绝经期女性人群逐渐庞大,围绝经期女性健康管理也变得愈发重要。围绝经期综合征可见于40~65岁女性群体,会严重影响患者的身心健康和生活质量。目的系统评价我国40~65岁女性人群围绝经期综合征的发生率。方法计算机检索PubMed、Embase、Web of Science、中国知网、万方数据知识服务平台、中国生物医学文献数据库和维普网,收集有关中国40~65岁女性围绝经期综合征发生情况的横断面研究,检索时间设置为建库至2023-02-01。由2名研究人员独立筛选文献,并对纳入文献进行数据提取和质量评价,使用Stata 17.0软件进行Meta分析。结果最终纳入62篇横断面研究,总样本量为82340例。Meta分析结果显示,我国40~65岁女性人群围绝经期综合征发生率为61.0%。亚组分析结果显示,40~45岁、>45~50岁、>50~55岁、>55~60岁、>60岁女性围绝经期综合征发生率分别为42.6%、53.8%、64.6%、59.7%、56.1%;月经状态为正常、紊乱、绝经的40~65岁女性围绝经期综合征发生率分别为43.6%、56.9%、61.3%;患慢性病、未患慢性病的40~65岁女性围绝经期综合征发生率分别为85.9%、68.3%;西南地区40~65岁女性围绝经期综合征发生率最高,为71.3%,华北、华东、华南、西北、东北、华中地区的发生率分别为57.4%、57.9%、50.5%、59.2%、69.5%、68.6%;文化程度为初中及以下、高中或中专、大学及以上的40~65岁女性围绝经期综合征发生率分别为54.1%、55.7%、49.6%。汉族、少数民族40~65岁女性围绝经期综合征发生率分别为62.1%、64.7%。结论我国40~65岁女性人群围绝经期综合征发生率高,其中>50~55岁、绝经、患慢性病、西南地区、文化程度为高中及以下、少数民族围绝经期综合发生率较高,应重视相关人群围绝经期综合征的预�Background With the rapid development of economy and society in China,the living standards and health care awareness have been improved significantly,the average life expectancy of our population is gradually prolonged,causing increasing population of perimenopausal women,therefore,the health management of perimenopausal women has become more important.Perimenopausal syndrome can be seen in women aged 40-65 years,which can seriously affect the physical and mental health and quality of life of patients.Objective To systematically review the incidence of perimenopausal syndrome in Chinese women aged 40-65 years.Methods PubMed,Embase,Web of Science,CNKI,Wanfang Data,CBM and VIP were searched by computer to collect cross-sectional studies on the occurrence of perimenopausal syndrome in Chinese women aged 40-65 years from inception to February 1,2023.Two investigators independently screened the literature,extracted data and evaluated the quality of included literature.Meta-analysis was performed using Stata 17.0 software.Results A total of 62 cross-sectional studies were included,with a total sample size of 82340 cases.Meta-analysis showed that the incidence of perimenopausal syndrome in Chinese women aged 40-65 years was 61.0%.The results of subgroup analysis showed that the incidence of perimenopausal syndrome in women aged 40-45 years,>45-50 years,>50-55 years,>55-60 years and>60 years was 42.6%,53.8%,64.6%,59.7%and 56.1%,respectively.The incidence of perimenopausal syndrome in women aged 40-65 years with normal,disordered and postmenopausal menstrual status was 43.6%,56.9%and 61.3%,respectively.The incidence of perimenopausal syndrome in women aged 40-65 years with and without chronic diseases was 85.9%and 68.3%,respectively.The incidence of perimenopausal syndrome was highest in women aged 40-65 years in Southwest China at 71.3%,and at 57.4%,57.9%,50.5%,59.2%,69.5%,and 68.6%in North,East,South,Northwest,Northeast,and Central China,respectively.The incidence of perimenopausal syndrome in women aged 40-65 years wit

关 键 词：围绝经期 更年期综合征 围绝经期综合征 女性 发生率 横断面研究 META分析 

分 类 号：R711.51[医药卫生—妇产科学]