金属有机框架固定化漆酶研究进展  

Progress of metal-organic framework immobilized laccase research

作　　者：雷长阳 郭彩丽 胡奇 LEI Changyang;GUO Caili;HU Qi(School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang 110016,China)

机构地区：[1]沈阳药科大学制药工程学院,辽宁沈阳110016

出　　处：《沈阳药科大学学报》2023年第6期818-830,共13页Journal of Shenyang Pharmaceutical University

基　　金：沈阳药科大学中青年教师事业发展支持计划(ZQN2016026);辽宁省科技厅博士启动基金项目(20180540034)。

摘　　要：目的通过综述金属有机框架材料(metal-organic frameworks,MOFs)固定化漆酶研究进展为后续MOFs固定化漆酶的选择和设计提供指导。方法利用Web of Science与中国知网等检索平台,查阅相关文献,总结近年来MOFs固定化漆酶的最新进展。结果本文综述了近年来MOFs固定化漆酶的研究进展和其活性评价方法,并且分析了在使用物理吸附法和共价结合法固定漆酶的过程中,漆酶投加量和固定化时间对固定化效率的影响,还介绍了固定化对漆酶最适pH和最适温度的改变,并且对漆酶和介体的共固定化进行了总结,最后,介绍了MOFs固定化漆酶在废水处理中的应用。结论MOFs因其高吸附容量和灵活的结构已成为漆酶固定化研究的热门载体。Objective To review the advances in laccase immobilization with metal-organic frameworks(MOFs)and provide a valuable guideline for the subsequent selection and design of MOFs for more targeted immobilization of laccase.Methods Web of Science and China National Knowledge Infrastructure(CNKI)were researched for related literatures,and the latest progress of laccase immobilization by metalorganic frameworks was summarized in recent years.Results The review summarized the recent advances in laccase immobilization and the evaluation methods of laccase activity.The effects of dosage and time on laccase immobilization through physical adsorption and covalent binding method were analyzed.The changes of optimum pH and temperature of laccase were summarized after immobilization.The co-immobilization of laccase and mediators were also reviewed.Finally,the application of immobilized laccase in wastewater treatment were introduced.Conclusion MOFs have been promising popular carriers for the high adsorption capacity and flexible structure.

关 键 词：漆酶 金属有机框架 固定化 生物催化 

分 类 号：TS201.2[轻工技术与工程—食品科学]