供、受体体质指数比值对公民逝世后器官捐献供肾移植后肾功能预后的影响  

Effect of body mass index ratio of donor and recipient on prognosis of renal function after donor kidney transplantation

作　　者：赵贺 秦兴松 秦威 孙东 蒋欣 Zhao He;Qin Xingsong;Qin Wei;Sun Dong;Jiang Xin(Organ Transplantation Center,Zhengzhou People’s Hospital,the Fifth Clinical Medical School of Henan University of Chinese Medicine,Zhengzhou 450003,China)

机构地区：[1]河南中医药大学第五临床医学院郑州人民医院器官移植中心,郑州450003

出　　处：《国际移植与血液净化杂志》2023年第2期27-30,共4页International Journal of Transplantation and Hemopurification

摘　　要：目的探讨供、受体体质指数(BMI)比值对公民逝世后器官捐献(DCD)供肾移植后肾功能的影响,以指导公民逝世器官捐献供肾时受者的选择。方法回顾性分析2015年1月至2017年6月期间在郑州人民医院成功施行DCD肾移植的供、受者临床资料。依据供、受者BMI比值四分位数将受者分为3组:A组:BMI比值≤0.97,B组:BMI比值0.97~1.28,C组:BMI比值>1.28。比较3组术后1周、1个月、6个月、12个月及24个月血肌酐(SCr)、肾小球滤过率(GFR)的变化。结果术后1个月、6个月、12个月B组SCr值均低于A组与C组,且组间差异有统计学意义(P<0.05);术后1个月、12个月B组GFR均高于A组与C组,组间差异有统计学意义(P<0.05)。术后24个月时3组SCr、GFR比较差异无统计学意义。结论B组受者肾功能恢复优于A组和C组。供、受者BMI比值介于0.97~1.28时移植肾功能及预后较好,应作为选择受者的一个参考指标。Objective To analyze the body mass index(BMI)ratio of donor and recipient on the renal function after donor kidney transplantation.Methods The clinical data of recipients and donors of kidney transplantation performed at Zhenzhou People’s Hospital from January 2015 to June 2017 were analyzed retrospectively.All the donor kidneys were from donation after citizens’death(DCD).The recipients were divided into three groups based on the quartiles of donor and recipient BMI ratio.Group A:BMI ratio≤0.97;Group B:BMI ratio between 0.97 and 1.28;Group C:BMI ratio>1.28.The renal function of the recipients were recorded at 1 week,1,6 and 12 months,and 1 year postoperatively.Results The serum creatinine(Scr)level in the Group B was lower than that in the Group A and Group C at 1,6 and 12 months after transplantation,and the differences were all significant(P<0.05).The estimated glomerular filtration rate(GFR)in the Group B was lower than that in the Group A and Group C at postoperative 1 and 12 months,and the differences were significant(P<0.05).There was no significant difference between the three groups in SCr and GFR at 2 years after transplantation.Conclusion The BMI ratio between donor and recipient was between 0.97 and 1.28,the function and prognosis of transplanted kidney were much better,which should be used as a reference index for selecting recipients.

关 键 词：肾移植 公民逝世后器官捐献 供、受体体质指数比值 移植肾功能 

分 类 号：R699.2[医药卫生—泌尿科学]