Selenium and human nervous system  

作　　者：Wenqiang Ding Shuang Wang Jiaxiang Gu Lei Yu 

机构地区：[1]Institute of Translational Medicine,Medical College,Yangzhou University,Yangzhou 225001,China [2]Department of Hand and Foot,Clinical Medical College,Yangzhou University,Yangzhou 225001,China [3]School of Chemistry and Chemical Engineering,Yangzhou University,Yangzhou 225002,China

出　　处：《Chinese Chemical Letters》2023年第7期11-16,共6页中国化学快报（英文版）

基　　金：Jiangsu Provincial Six Talent Peaks Project (No. XCL090);the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) for support;support of the fund of the joint-laboratory of Shanghai Dingya Pharmaceutical Chemical Technology Co., Ltd. with Yangzhou University (2022-2027)。

摘　　要：Selenium plays various biological functions in the form of selenoprotein in human body. Brain is one of the most abundant organs of selenoprotein, which plays an important role in maintaining brain redox homeostasis, signal transduction pathway regulation and neuroimmune regulation. Yet, nano-selenium have attracted much attention for their high bioavailability and low toxicity. Nano-selenium are of great application potential in field of biomedical nervous system. Recently, investigation on selenoprotein and nano-selenium has gradually become a new hotspot for the important functions of selenium in human nervous system. In this article, we wish to review recent progresses and give a perspective.

关 键 词：SELENIUM Nervous system SELENOPROTEIN NANO-SELENIUM Plumbism Brain function 

分 类 号：R338[医药卫生—人体生理学]