孕妇流感疫苗接种相关研究进展  

Progress in research of influenza vaccination in pregnant women

作　　者：范思萌 杨孝坤 赵宏婷 秦颖[1] 郑建东[1] 彭质斌[1] 张彦平[1] 冯子健[2] Fan Simeng;Yang Xiaokun;Zhao Hongting;Qin Ying;Zheng Jiandong;Peng Zhibin;Zhang Yanping;Feng Zijian(Division of Infectious Diseases,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Chinese Center for Disease Control and Prevention,Beijing 102206,China)

机构地区：[1]中国疾病预防控制中心传染病管理处,北京102206 [2]中国疾病预防控制中心,北京102206

出　　处：《中华流行病学杂志》2023年第7期1157-1162,共6页Chinese Journal of Epidemiology

基　　金：中美新发和再发传染病合作项目(6NU2GGH000961-05-02);公共卫生应急反应机制运行项目(131031001000210001,102393220020010000017)。

摘　　要：流感是由流感病毒引起的急性呼吸道传染病,妊娠期间因生理和免疫功能的变化,孕妇罹患流感及发生相关并发症的风险较高。接种流感疫苗是预防流感的有效手段。WHO和许多国家均将孕妇列为流感疫苗接种的优先推荐人群,但目前我国孕妇流感疫苗接种率偏低,且部分产品使用说明将孕妇列为接种禁忌人群,推动孕妇流感疫苗接种工作仍存在诸多挑战。本文就近年来国内外流感对孕妇及其胎儿的影响以及孕妇接种流感疫苗研究进展进行综述,并针对目前孕妇流感疫苗接种的现状,提出促进孕妇接种流感疫苗的策略并进行探讨,以期为我国相关工作的开展和政策制定提供参考。Influenza is an acute respiratory infectious disease caused by influenza virus.Pregnancy is associated with physiologic and immunological changes that may increase the risk for influenza virus infection and influenza-related complications.Influenza vaccination is the most effective way to prevent influenza virus infection.WHO and many countries have classified pregnant women as a priority population for influenza vaccination,however,there are still many challenges for promoting influenza vaccination in pregnant women in China,influenza vaccination coverage in pregnant women remains low and some influenza vaccine package inserts list pregnancy as an absolute contraindication.In this paper,we summarize the research progress in the effects of influenza infection and influenza vaccination during pregnancy both at home and abroad,then discuss the strategies to promote influenza vaccination in pregnancy for the purpose of providing reference for the related research and policy development in China.

关 键 词：流感 孕妇 流感疫苗 

分 类 号：R186[医药卫生—流行病学]