前列腺癌根治术联合盆腔淋巴结清扫术治疗前列腺癌对性功能影响的回顾性研究  

A retrospective study on the effects of radical prostatectomy combined with pelvic lymph node dissection on sexual function in prostate cancer

作　　者：魏立[1] 李斌[1] 范丽娜[1] WEI Li;LI Bin;FAN Lina(Department of Urology,Yuyao People′s Hospital,Yuyao 315400,Zhejiang,China)

机构地区：[1]余姚市人民医院泌尿外科,浙江余姚315400

出　　处：《中国性科学》2023年第7期12-16,共5页Chinese Journal of Human Sexuality

摘　　要：目的探究前列腺癌根治术联合盆腔淋巴结清扫术治疗前列腺癌对其性功能的影响。方法回顾性分析2015年5月至2020年5月余姚市人民医院诊治的63例行前列腺癌根治术联合盆腔淋巴结清扫术治疗的前列腺癌患者的临床资料。根据治疗方式分为常规组(n=32)和改良组(n=31),分析比较两组围手术期情况,采用国际勃起功能指数-5(IIEF-5)评估术后患者性功能恢复情况,采用国际尿失禁咨询委员会尿失禁问卷表简表(ICI-Q-SF)评估术后患者控尿功能。结果改良组手术时间长于常规组,术中出血量少于常规组,术后肠道功能恢复时间和留置导尿管时间短于常规组,差异均具有统计学意义(P<0.05)。两组术前IIEF-5、ICI-Q-SF评分比较,差异无统计学意义(P>0.05);改良组术后3、6、12个月的IIEF-5评分均高于常规组,改良组术后3、6、12个月的ICI-Q-SF评分均低于常规组,差异均具有统计学意义(P<0.05)。结论改良式腹腔镜下前列腺癌根治术联合盆腔淋巴结清扫术对前列腺癌患者的性功能和控尿恢复能力优于传统腹腔镜下前列腺癌根治术联合盆腔淋巴结清扫术。Objective To explore the effects of radical prostatectomy combined with pelvic lymph node dissection(PLND)on sexual function in prostate cancer(PC).Methods A retrospective analysis was performed on the clinical data of 63 patients with PC undergoing radical prostatectomy combined with PLND in Yuyao People′s Hospital between May 2015 and May 2020.According to different treatment methods,they were divided into routine group(n=32)and modified group(n=31).The perioperative conditions in the two groups were analyzed and compared.The postoperative recovery of sexual function was evaluated by international index of erectile function-5(IIEF-5).The urinary continence was evaluated by international consultation on incontinence questionnaire-urinary incontinence short form(ICI-Q-SF).Results The operation time in modified group was longer than that in routine group,intraoperative blood loss was less than that in routine group,postoperative recovery time of intestinal function and indwelling catheter time were shorter than those in routine group(P<0.05).There was no significant difference in scores of IIEF-5 and ICI-Q-SF between the two groups before surgery(P>0.05).At 3,6 and 12 months after surgery,IIEF-5 scores in modified group were higher than those in routine group,while ICI-Q-SF scores were lower than those in routine group(P<0.05).Conclusions The modified laparoscopic radical prostatectomy combined with PLND is superior to traditional laparoscopic radical resection combined with PLND in terms of the recovery of sexual function and urinary continence in PC patients.

关 键 词：前列腺癌 前列腺癌根治术 盆腔淋巴结清扫术 性功能 

分 类 号：R697[医药卫生—泌尿科学]