针灸相关疗法治疗慢性前列腺炎有效性的网状Meta分析  

The efficacy of acupuncture-related therapies for chronic prostatitis:a network Meta-analysis

作　　者：夏高艳 刘明[2] 丁小姣 宁容容 齐雨欣 肖培根 叶险峰 XIA Gaoyan;LIU Ming;DING Xiaojiao;NING Rongrong;QI Yuxin;XIAO Peigen;YE Xianfeng(Master Degree Candidate of Acupuncture and Tuina Enrolled in 2021,the Third School of Clinical Medicine,Henan University of Chinese Medicine,Zhengzhou 450046,Henan,China;Department of Rehabilitation,Third Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450008,Henan,China;Master Degree Candidate of Acupuncture and Tuina Enrolled in 2020,the Third School of Clinical Medicine,Henan University of Chinese Medicine,Zhengzhou 450046,Henan,China;Master Degree Candidate of Acupuncture and Tuina Enrolled in 2022,the Third School of Clinical Medicine,Henan University of Chinese Medicine,Zhengzhou 450046,Henan,China;School Production Management Company,Henan University of Chinese Medicine,Zhengzhou 450046,Henan,China)

机构地区：[1]河南中医药大学第三临床医学院,郑州450046 [2]河南中医药大学第三附属医院康复科,郑州450008 [3]河南中医药大学校产经营管理公司,郑州450046

出　　处：《中国性科学》2023年第7期130-137,共8页Chinese Journal of Human Sexuality

基　　金：河南省中医药科学研究专项课题(20-21ZY2129)。

摘　　要：目的采用贝叶斯网状Meta分析的方法系统评价和比较不同针灸相关疗法治疗慢性前列腺炎的效果。方法系统检索PubMed、Cochane Library、中国知网(CNKI)、万方数据库(Wanfang)、维普数据库(VIP)及中国生物医学文献数据库(CBM)中关于针灸相关疗法治疗慢性前列腺炎的随机对照试验(RCT),检索时限为2000年1月1日至2022年1月19日。先由2名研究者独立筛选文献、提取数据及应用Cochrane系统评价手册评估文献质量,然后使用R4.2.0软件进行数据分析。结果最终纳入38篇RCT研究,总样本量3313例,共涉及26种干预措施;网状Meta分析结果显示,在降低慢性前列腺炎症状指数(NIH-CPSI)评分方面,效果最优的前3位干预措施依次为:针刺+西药+中药灌肠、针刺+温热灸、针刺+电针+中成药。在提高临床疗效总有效率方面,效果最优的前3位干预措施依次为:针刺+西药+中药灌肠、针刺+中药+中药灌肠、针刺+中成药。结论与常规西药治疗方案比较,针灸相关疗法在改善慢性前列腺炎相关症状,以及提高临床疗效方面具有良好的效果;联合疗法治疗效果优于单一疗法。由于纳入文献的研究设计及样本量等存在局限性,本研究的结论还需大量的多中心、大样本RCT研究进一步验证。Objective To systematically evaluate and compare the efficacy of different acupuncture-related therapies for chronic prostatitis(CP)using Bayesian network Meta-analysis.Methods This paper systematically searched for randomized controlled trials(RCTs)of acupuncture-related therapies for chronic prostatitis from databases of PubMed,Cochrane Library,Chinese National Knowledge Infrastructure(CNKI),WanFang Data,China Science and Technology Journal Database(VIP)and China Biology Medicine(CBM)from January 1,2000 to January 19,2022.Two researchers screened literature,performed data extraction,and applied the Cochrane Handbook′s to assess the quality of the literature independently.Data analysis was performed using R4.2.0 sof tware.Results 38 RCTs were finally included,with a total sample size of 3,313 patients,involved a total of 26 interventions.The results showed that in terms of reducing the national institute of health-chronic prostatitis symptom index(NIH-CPSI)scores,the top 3 intervention with best effect were acupuncture+western medicine+Chinese medicine enema,acupuncture+warm moxibustion,acupuncture+electroacupuncture+Chinese patent medicine.In terms of improving overall efficacy rate,the top 3 intervention with best effect were acupuncture+western medicine+Chinese medicine enema,acupuncture+Chinese medicine+Chinese medicine enema,acupuncture+Chinese patent medicine.Conclusions Compared to conventional western medicine treatment,acupuncture-related therapies are more effective in relieving symptoms associated with CP and increasing clinical efficacy,and combination therapies are superior to monotherapy.Due to the limitations of the study design and sample size of included study,the conclusions of this study need to be further confirmed by the multicenter,large-sample RCTs.

关 键 词：慢性前列腺炎 针灸相关疗法 临床疗效 慢性前列腺炎症状指数评分 网状Meta分析 

分 类 号：R697[医药卫生—泌尿科学]