咽鼓管功能对突发性感音神经性聋患者内镜下鼓室内注射效果的预测价值  

Predictive value of eustachian tube function for endoscopic intra tympanic injection in patients with sudden sensorineural deafness

作　　者：王昌阳[1] 慈军[1] 管骅[1] WANG Changyang;CI Jun;GUAN Hua(Department of Otorhinolaryngology,Zhejiang Integrated Traditional Chinese and Western Medicine Hospital,Hangzhou,Zhejiang 310000,China)

机构地区：[1]浙江省中西医结合医院耳鼻咽喉科,浙江杭州310000

出　　处：《中华全科医学》2023年第8期1322-1325,共4页Chinese Journal of General Practice

基　　金：浙江省医药卫生科技计划项目(2020KY740)。

摘　　要：目的通过检测突发性感音神经性聋患者咽鼓管功能,评估其对内镜下鼓室内注射效果的预测价值。方法选取2021年2月-2022年8月于浙江省中西医结合医院接受内镜下鼓室内注射的突发性感音神经性聋患者115例,根据治疗2周后纯音听阈检测结果分为有效组(听力提高≥15 dB)和无效组(听力提高<15 dB)。采用多因素logistic回归分析影响突发性感音神经性聋患者内镜下鼓室内注射效果的相关因素,绘制ROC曲线分析咽鼓管功能对内镜下鼓室内注射效果的预测价值。结果治疗2周后,81例听力较治疗前提高≥15 dB为有效组,其余34例听力提高<15 dB为无效组。无效组年龄、受损频率听阈、咽鼓管功能评分水平较有效组高(P<0.05);多因素logistic回归分析显示:年龄(OR=1.056,95%CI:1.022~1.155)、受损频率听阈(OR=1.042,95%CI:1.006~1.079)、咽鼓管功能评分(OR=4.412,95%CI:2.247~8.666)为内镜下鼓室内注射效果的影响因素(P<0.05)。ROC曲线显示,咽鼓管功能评分预测内镜下鼓室内注射效果的AUC为0.812(95%CI:0.728~0.879),显著高于年龄[0.665(95%CI:0.571~0.750)]、受损频率听阈[0.667(95%CI:0.573~0.752),P<0.05]。结论咽鼓管功能对突发性感音神经性聋患者内镜下鼓室内注射效果预测价值相对较高。Objective To evaluate the predictive value of the eustachian tube for the effect of endoscopic intra tympanic injection through detecting the function of the eustachian tube in patients with sudden sensorineural deafness.Methods A total of 115 patients with sudden senineural deafness who received endoscopic tympanic injection in Zhejiang Hospital of Integrated Traditional and Western Medicine from February 2021 to August 2022 were selected.According to the pure tone hearing threshold detection results two weeks after treatment,they were divided into effective group(hearing improvement≥15 dB)and ineffective group(hearing improvement<15 dB).Multivariate logistic regression was used to analyze the related factors affecting the effect of endoscopic tympanic injection in patients with sudden senineural deafness,and ROC curve was drawn to analyze the predictive value of eustachian tube function on the effect of endoscopic tympanic injection.Results After 2 weeks of treatment,81 cases of hearing improvement≥15 dB compared with before treatment were effective group,and the remaining 34 cases of hearing improvement<15 dB were ineffective group.The age,impaired frequency threshold and eustachian tube function score of ineffective group were higher than those of effective group(P<0.05).Multivariate logistic regression analysis showed that:Age(OR=1.056,95%CI:1.022-1.155),impaired frequency threshold(OR=1.042,95%CI:1.006-1.079),eustachian tube function score(OR=4.412,95%CI:2.247-8.666)were the risk factors for endoscopic tympanic injection effect(P<0.05).ROC curve showed that the prediction AUC of endoscopic tympanic injection effect was 0.812(95%CI:0.728-0.879),which was significantly higher than that of age(0.665,95%CI:0.571-0.750)and impaired frequency hearing threshold(0.667,95%CI:0.573-0.752),P<0.05.Conclusion The function of eustachian tube is relatively valuable in predicting the effect of endoscopic tympanic injection in patients with sudden senineural deafness.

关 键 词：咽鼓管功能 突发性感音神经性聋 内镜治疗 预测 

分 类 号：R764.431[医药卫生—耳鼻咽喉科]