沉香汤治疗胃脘痛疗效及对中医证候、胃黏膜的影响  

Curative Effect of Chenxiang Decoction(沉香汤)on Epigastric Pain and The Influence on Traditional Chinese Medicine Syndromes and Gastric Mucosa

作　　者：丘文戈[1] 李映姗[1] 钟启腾[1] 梁玉华[1] 李慧 李亦聪[1] QIU Wenge;LI Yingshan;ZHONG Qiteng;LIANG Yuhua;LI Hui;LI Yichong(Huizhou Central People's Hospital,Huizhou 516001,Guangdong,China)

机构地区：[1]惠州市中心人民医院,广东惠州516001

出　　处：《中华中医药学刊》2023年第7期222-225,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(20221402);惠州市科学技术局项目(2021WC0106374)。

摘　　要：目的 研究沉香汤联合常规西医治疗胃脘痛患者的临床疗效,及其对患者中医证候和胃黏膜的影响。方法 选取惠州市中心人民医院2020年9月1日—2021年3月31日治疗的120例胃脘痛患者,将其按随机数字表法分为观察组和对照组,每组60例,对照组患者接受常规西医药物治疗,观察组患者在对照组基础上联合沉香汤治疗,比较两组患者的临床疗效、中医证候积分、胃黏膜情况以及不良反应等。结果 观察组患者治疗总有效率显著高于对照组患者[91.67%(55/60)vs 73.33%(44/60)](P<0.05);接受治疗后,两组患者各中医证候积分均显著降低(P<0.05),且观察组患者治疗后各中医证候积分均显著低于对照组(P<0.05);观察组患者治疗前后胃黏膜糜烂、出血及萎缩分别减少7例、17例、18例,改善率分别为70.00%、85.00%、87.50%,对照组患者治疗前后胃黏膜糜烂、出血及萎缩分别减少5例、16例、12例,改善率分别为55.56%、69.57%、63.64%,两组胃黏膜糜烂、出血及萎缩改善率差异无统计学意义(P>0.05);两组患者治疗期间不良反应发生率差异无统计学意义[6.67%(4/60)vs 5.00%(3/60)](P>0.05)。结论 沉香汤联合常规西医治疗胃脘痛患者临床疗效和安全性较好,可有效改善患者症状及胃黏膜情况。Objective To study the clinical effect of Chenxiang Decoction(沉香汤)combined with conventional western medicine in the treatment of patients with epigastric pain,and the effect on TCM syndromes and gastric mucosa.Methods A total of 120 patients with epigastric pain who were treated from Huizhou Central People's Hospital from September 1,2020 to March 31,2021 were selected.They were divided into the observation group and the control group by random number table method,with 60 cases in each group.Patients in the control group were treated with conventional western medicine,and those in the observation group were treated with Chenxiang Decoction based on the treatment of the control group.The clinical effects,TCM syndrome scores,gastric mucosal conditions and adverse reactions were compared between the two groups.Results The total treatment response rate of the observation group was significantly higher than that of the control group[91.67%(55/60)vs 73.33%(44/60)](P<0.05).After treatment,TCM syndrome scores of the two groups were significantly reduced(P<0.05),and the scores of the observation group were significantly lower than those of the control group(P<0.05).There was no statistically significant difference in the improvement rates of gastric mucosal erosion,bleeding or atrophy between the observation group and the control group(55.56%;85.00%vs 69.57%;87.50 vs 63.64%)(P>0.05).The incidence rates of adverse reactions in the two groups were similar[6.67%(4/60)vs 5.00%(3/60)](P>0.05).Conclusion Self-made Chenxiang Decoction combined with conventional western medicine is effective and safe in the treatment of patients with epigastric pain,which can effectively improve the symptoms and gastric mucosal conditions.

关 键 词：胃脘痛 沉香汤 疗效 中医证候 胃黏膜 

分 类 号：R256.33[医药卫生—中医内科学]