成人原发性肾病综合征激素维持治疗阶段中医体质与证型的相关性分析  

Correlation Analysis between TCM Constitution and Syndrome Types in Adults with Primary Nephrotic Syndrome Hormone Maintenance Therapy

作　　者：陈淑园 许筠 张茹 丁文君[3] CHEN Shuyuan;XU Yun;ZHANG Ru;DING Wenjun(Gansu University of Traditional Chinese Medicine,Gansu Lanzhou 730030,China;Lanzhou First People’s Hospital,Gansu Lanzhou 730030,China;Gansu Provincial Hospital of Traditional Chinese Medicine,Gansu Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学中西医结合学院,甘肃兰州730030 [2]兰州市第一人民医院,甘肃兰州730030 [3]甘肃省中医院,甘肃兰州730000

出　　处：《中医药临床杂志》2023年第7期1365-1370,共6页Clinical Journal of Traditional Chinese Medicine

基　　金：甘肃省中医药管理局项目(GZK-2019-72);兰州市卫生健康科技发展项目(2019-017);甘肃中医药大学研究生创新创业基金项目(2022CX43)。

摘　　要：目的:观察成人原发性肾病综合征(PNS)患者在激素维持治疗阶段中医体质与证型的相关性。方法:选取176例成人PNS激素维持治疗阶段患者为研究对象,辨识中医体质与证型,分析二者相关性。结果:176例成人PNS患者体质辨识多见平和质、阳虚质、气虚质、阴虚质、湿热质、血瘀质;中医证型常见脾肾阳虚证、脾肾气虚证、气阴两虚证、湿热证、血瘀证。“三辨”分析:平和质与脾肾气虚证、脾肾阳虚证、湿热证呈正相关;阳虚质与脾肾阳虚证、脾肾气虚证存在正相关;气虚质与脾肾气虚证、肺脾气虚证呈正相关;阴虚质与气阴两虚证、肝肾阴虚证正相关;湿热质与湿热证、水湿证呈正相关;血瘀质与血瘀证存在正相关(P<0.05或P<0.01)。结论:成人PNS激素维持治疗阶段患者中医体质与证型之间存在相关性,通过辨体-辨病-辨证“三辨”模式,对临床早期预防、辨证论治及个体化诊疗具有一定价值。Objective:To observe the correlation between TCM constitution and syndrome types in adult patients with primary nephrotic syndrome(PNS)during hormone maintenance therapy.Methods:176 adult patients with PNS hormone maintenance therapy were selected as the research objects,TCM constitution and syndrome types were identified,and their correlation was analyzed.Results:The constitution identification of 176 adult PNS patients was mostly peaceful,Yang-deficiency,Qi-deficiency,Yin-deficiency,damp-heat,blood stasis;Deficiency syndrome,damp-heat syndrome,blood stasis syndrome.Analysis of“Three Differentiation”:Peaceful quality is positively correlated with spleen-kidney Qi deficiency,spleen-kidney yang deficiency,and damp-heat syndrome;yang-deficiency quality is positively correlated with spleen-kidney yang deficiency and spleen-kidney Qi-deficiency;lung Qi-deficiency syndrome were positively correlated;Yin-deficiency constitution was positively correlated with Qi-Yin deficiency syndrome and liver-kidney-yin deficiency syndrome;damp-heat constitution was positively correlated with damp-heat syndrome and water-dampness syndrome;blood stasis constitution was positively correlated with blood stasis syndrome(P<0.05,P<0.01).Conclusion:There is a correlation between TCM constitution and syndrome types in adult patients with PNS hormone maintenance therapy.Through the“three discrimination”mode of body differentiation-disease differentiation-syndrome differentiation,it has certain value for early clinical prevention,syndrome differentiation and treatment,and individualized diagnosis and treatment.

关 键 词：原发性肾病综合征 激素维持治疗阶段 中医体质 中医证型 

分 类 号：R692[医药卫生—泌尿科学]