宣肺清热化湿法治疗皖北地区新型冠状病毒感染轻型、普通型患者临床观察  

Clinical Observation on the Treatment of Mild and Common Novel Coronavirus Infection in Northern Anhui by Promoting Lung and Clearing Heat and Dampness

作　　者：孙宇洁 许文彬 马守亮[2] 郭锦晨 韩亚军 张雷[4] 施卫兵[2] SUN Yujie;XU Wenbin;MA Shouliang;GUO Jinchen;HAN Yajun;ZHANG Lei;SHI Weibing(Anhui University of Chinese Medicine,Anhui Hefei 230038,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Anhui Hefei 230031,China;Key Laboratory of Xin’an Medical Science,Ministry of Education of Anhui University of Chinese Medicine,Anhui Hefei 230012,China;Suzhou Municipal Hospital,Anhui Suzhou 234000,China)

机构地区：[1]安徽中医药大学第一临床医学院,安徽合肥230038 [2]安徽中医药大学第一附属医院,安徽合肥230031 [3]安徽中医药大学新安医学教育部重点实验室,安徽合肥230012 [4]安徽省宿州市立医院,安徽宿州234000

出　　处：《中医药临床杂志》2023年第7期1416-1420,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：2022年安徽省科技厅新冠病毒科研应急攻关专项(2022e07020081、2022e07020082);长三角名中医工作室建设项目(皖财社[2021]324号);安徽省施卫兵名中医工作室建设项目(安徽省卫健委中发展[2020]10号)。

摘　　要：目的:观察宣肺清热化湿法对40例皖北地区新型冠状病毒感染(原名:新型冠状病毒肺炎)轻型及普通型患者的临床疗效。方法:纳入安徽省宿州市第三人民医院救治的新型冠状病毒感染轻型及普通型患者,所有患者均将宣肺清热化湿法(原清肺排毒汤基础上加清热化湿之品)。比较和分析治疗前后各项临床指标,包括住院时间、病毒转阴时间、血常规、生化指标、中医证候评分及有效率等,采用SPSS 26.0统计软件对各指标数据进行统计描述和分析。结果:共纳入40例患者,所有患者经过治疗病毒核酸检测均转阴后出院,轻型平均住院时间(9.81±2.90)d,连续2次核酸转阴时间(11.11±4.11)d,有效率85.19%。普通型平均住院时间(10.54±2.54)d,连续2次核酸转阴时间(10.23±2.74)d,有效率84.62%。治疗后白细胞计数升高、淋巴细胞百分比升高、C反应蛋白计数降低,前后比较差异有统计学意义。治疗过程中密切关注肝肾功能,未发现造成肝肾损伤者。结论:宣肺清化法治疗皖北地区新型冠状病毒感染轻型及普通型患者收效明显且ALT、AST等肝功能指标均值在正常范围内,研究者临床观察治疗全程未发现不良反应,安全性有保证。Objective:To observe the clinical curative effect of Xuanfei Qingrehuashi method on 40 cases of mild and common patients with novel coronavirus infection(formerly known as novel coronavirus pneumonia)in northern Anhui.Methods:Patients with mild and common type of novel coronavirus infection who were treated in the Third People’s Hospital of Suzhou City,Anhui Province were included.All patients were treated with Xuanfei Qingrehumidity Method(the original Qingfei Paidu Decoction was added with heat-clearing and dampness-removing products).The clinical indicators before and after treatment were compared and analyzed,including hospitalization time,virus negative time,blood routine,biochemical indicators,TCM syndrome score and effective rate,etc.SPSS 26.0 statistical software was used to describe and analyze the data of each indicator.Results:A total of 40 patients were included,and all patients were discharged after the virus nucleic acid test turned negative after treatment.The average hospitalization time for mild cases was(9.81±2.90)days,and the time for two consecutive nucleic acid turning negatives was(11.11±4.11)days,and the effective rate was 85.19%..The average length of hospitalization for common type was(10.54±2.54)days,and the time for two consecutive nucleic acid conversions was(10.23±2.74)days,with an effective rate of 84.62%.After treatment,the white blood cell count increased,the percentage of lymphocytes increased,and the C-reactive protein count decreased,and the difference was statistically significant.Liver and kidney functions were closely monitored during treatment,and no liver or kidney damage was found.Conclusion:Xuanfei Qinghua method has obvious effect in the treatment of mild and common patients with new coronavirus infection in northern Anhui,and the average values of liver function indexes such as ALT and AST are within the normal range.The researchers did not find any adverse reactions in the whole process of clinical observation and treatment,and the safety is good.ensure.

关 键 词：新型冠状病毒 轻型 普通型 皖北地区 宣肺清化法 临床观察 

分 类 号：R256.1[医药卫生—中医内科学]