抽提透刺针法为主改善小脑梗死患者平衡功能及对其血管新生、脑血流动力学的影响  

Improvement of Balance Function and Effect on Angiogenesis and Cerebral Hemodynamics in Patients with Cerebellar Infarction by Main Method of Lifting Point-Toward-Point Needling Method

作　　者：孙金鹏[1] 崔友祥[1] 陈华[1] 王磊磊 刘国华[1] 胡方梅[1] SUN Jinpeng;CUI Youxiang;CHEN Hua;WANG Leilei;LIU Guohua;HU Fangmei(Cangzhou Hospital of Integrated TCM-WMoHebei,Cangzhou Hebei 061001,China)

机构地区：[1]河北省沧州中西医结合医院,河北沧州061001

出　　处：《中医药导报》2023年第7期106-110,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：河北省中医药类科研计划项目(2018500)。

摘　　要：目的:探讨以抽提透刺针法为主对小脑梗死患者平衡功能的改善作用及对其血管新生指标、脑血流动力学的影响。方法:将84例小脑梗死患者随机分为对照组与透刺组,各42例。对照组给予常规西药治疗结合传统平衡康复训练加肌力训练,透刺组在对照组基础上给予抽提透刺针法治疗,1次/d,每5 d休息2 d,连续治疗4周。比较两组患者的Berg平衡量表(BBS)评分、脑卒中患者姿势评定量表(PASS)评分、徒手肌力评定量表(MMT)评分、改良Ashworth量表评分、Fug-Meyer量表(FMA)评分、改良Barthel指数评定量表(MBI)评分。多普勒超声探测脑血流动力参数,ELISA检测血清中血管内皮生长因子(VEGF)、碱性成纤维细胞生长因子(bFGF)、血小板源性生长因子(PDGF)及血管生成素-1(Ang-1)水平。结果:治疗后透刺组患者BBS评分、PASS评分、MMT评分、FMA及MBI评分均高于对照组(P<0.05);透刺组与对照组患者改良Ashworth量表评分比较,差异无统计学意义(P>0.05)。治疗后透刺组患者收缩期峰值流速(Vs)、舒张期峰值流速(Vd)、平均流速(Vm)均高于对照组(P<0.05),而阻力指数(RI)低于对照组(P<0.05);透刺组患者VEGF、PDGF、Ang-1值均高于对照组(P<0.05),而bFGF值低于对照组(P<0.05)。结论:以抽提透刺针法为主能够明显改善小脑梗死患者的平衡功能,提高患者的肢体运动功能及日常生活活动能力,该治疗作用可能是通过调控脑血管新生、改善脑血流动力学实现的。Objective:To investigate the effect of the main method of lifting point-toward-point needling method on balance function,angiogenesis index and cerebral hemodynamics in patients with cerebellar infarction.Methods:A total of 84 patients with cerebellar infarction were enrolled and randomly divided into control group and point-toward-point needling group,with 42 cases in each group.The control group was treated with conventional western medicine and traditional balance rehabilitation training,while the point-toward-point needling group was treated with lifting point-toward-point needling method on the basis of the control group,once a day,with a 2-day rest every 5 days,for 4 weeks.The BBS,PASS,MMT,modified Ashworth,FMA and MBI scores were compared between the two groups.Doppler ultrasound is used to detect cerebral hemodynamic parameters.Serum levels of VEGF,bFGF,PDGF and Ang-1 were detected by ELISA.Results:After treatment,the point-toward-point needling group showed higher BBS,PASS,MMT,FMA and MBI scores than control group(P<0.05),and there was no significant difference in Ashworth scale score between the two group(P>0.05).After treatment,the point-toward-point needling group showed higher Vs,Vd and Vm values than control group(P<0.05),while lower RI value than control group(P<0.05).After treatment,the point-toward-point needling group showed higher levels of VEGF,PDGF and Ang-1 than control group(P<0.05),while lower level of bFGF than control group(P<0.05).Conclusion:The main method of lifting point-toward-point needling method can significantly improve the balance function,improve the limb motor function and activities of daily living in patients with cerebellar infarction,which may be achieved by regulating cerebral angiogenesis and improving cerebral hemodynamics.

关 键 词：小脑梗死 抽提透刺针法 平衡功能 血管新生 脑血流动力学 临床研究 

分 类 号：R246.6[医药卫生—针灸推拿学]