海藻多糖的抗病毒活性及其机制的研究进展  

Research progress in antiviral activities of seaweed polysaccharides and related mechanism

作　　者：高星熠 张诗悦 张伟[2,3] 张亮 陈九[2,3] 闫滨 杨宏军 GAO Xing-yi;ZHANG Shi-yue;ZHANG Wei;ZHANG Liang;CHEN Jiu;YAN Bin;YANG Hong-jun(Shandong University of Traditional Chinese Medicine,Jinan 250100;Shandong Key Laboratory of Animal Disease Control and Breeding,Institute of Animal Science and Veterinary Medicine,Shandong Academy of Agricultural Sciences,Jinan 250100;Key Laboratory of Livestock and Poultry Multi-omics of MARA,Jinan 250100)

机构地区：[1]山东中医药大学,济南250100 [2]山东省农业科学院畜牧兽医研究所,山东省畜禽疫病防治与繁育重点实验室,济南250100 [3]农业农村部畜禽生物组学重点实验室,济南250100

出　　处：《中南药学》2023年第7期1852-1858,共7页Central South Pharmacy

基　　金：国家现代农业产业技术体系资助(No.CARS36);山东省重点研发计划(乡村振兴科技创新提振行动计划)项目“预制菜全链条智慧生产技术创新与应用”(No.2022TZXD0021)。

摘　　要：海藻多糖是海藻的主要组成成分,近年来受到国内外学者的高度重视,研究发现,海藻多糖结构复杂,具有多种生理活性,尤其具备显著的抗病毒活性。本文主要对国内外海藻多糖的抗病毒活性和相关作用机制研究进展进行总结,并对海藻多糖混合物的分离纯化方式进行总结和整理,以期为海藻多糖抗病毒活性的研究提供发展方向,并对关键性问题提供建议,促进海藻多糖在抗病毒新药研发方面发挥更重要的作用。Seaweed polysaccharide is the main component of seaweed.In recent years,it has been deeply valued by scholars at home and abroad.Seaweed polysaccharide has complex structure and various physiological activities,especially significant antiviral activity.This paper mainly summarized the research progress in the antiviral activity of seaweed polysaccharides and related mechanism at home and abroad,and summarized the separation and purification methods of seaweed polysaccharide mixtures.We aim to provide reference for the study of the antiviral activity of seaweed polysaccharide and determine its important role in the development of new antiviral drugs.

关 键 词：海藻多糖 抗病毒活性 机制 研究进展 

分 类 号：R932[医药卫生—生药学] R285[医药卫生—药学]