肺炎克雷伯菌生物膜治疗的研究进展  

Recent advances in the treatment of Klebsiella pneumoniae biofilms

作　　者：周彤 周秀娟 龙坤兰 陈骏[1] 高培阳[1] Zhou Tong;Zhou Xiu-juan;Long Kun-lan;Chen Jun;Gao Pei-yang(Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075)

机构地区：[1]成都中医药大学附属医院,成都610075

出　　处：《中国抗生素杂志》2023年第6期636-642,共7页Chinese Journal of Antibiotics

基　　金：国家自然科学基金面上项目(No.81873298);四川省中医药管理局重大疾病中医药防治中心建设与管理项目(No.2100601)。

摘　　要：肺炎克雷伯菌作为医院感染的主要病原体之一,具有聚集成生物膜的能力,极易附着在医疗设备上,是多种慢性感染的重要原因。肺炎克雷伯菌生物膜感染极难治愈,传统抗生素治疗并不能有效地改善患者的预后。因此,目前亟需开发治疗肺炎克雷伯菌生物膜的新方法。本文就近几年肺炎克雷伯菌生物膜的治疗作一综述,旨在为开发肺炎克雷伯菌生物膜新的治疗方法提供思路。Klebsiella pneumoniae,as one of the main pathogens of nosocomial infection,has the ability to aggregate into biofilms and is easily attached to medical equipment,which is an important cause of various chronic infections.Klebsiella pneumoniae biofilm infection is extremely difficult to cure,and traditional antibiotic treatment cannot effectively improve the prognosis of patients.Therefore,it is urgent to develop new treatment methods for Klebsiella pneumoniae biofilms.This paper makes a summary on advances in the treatment of Klebsiella pneumoniae biofilms to provide new ideas for it.

关 键 词：肺炎克雷伯菌 生物膜 治疗 研究进展 

分 类 号：R978.1[医药卫生—药品]