毛麝香乙酸乙酯部位的化学成分研究  

Study on Chemical Constituents of Ethyl Acetate Site of Ethanol Extract of Adenosma glutinosum(L.)Druce

作　　者：王呈文[1] 钟秋梅 江炜钰 蔡映举 WANG Chengwen;ZHONG Qiumei;JIANG Weiyu;CAI Yingju(Shantou Polytechnic,Shantou 515000,China)

机构地区：[1]汕头职业技术学院,广东汕头515000

出　　处：《生物化工》2023年第3期41-44,50,共5页Biological Chemical Engineering

摘　　要：目的:研究毛麝香全草乙醇提取物的乙酸乙酯萃取部位的化学成分。方法:通过硅胶柱色谱和葡聚糖凝胶柱色谱等分离方法进行分离纯化,运用波谱手段、理化性质和文献对照鉴定各单体化合物的结构。结果:从毛麝香全草乙醇提取物的乙酸乙酯部位中分离出16个化合物,分别鉴定为7-羰基-β-谷甾醇(1)、丁香酚(2)、羽扇豆醇(3)、对羟基肉桂酸甲酯(4)、栀子酸(5)、木犀草素(6)、芹菜素(7)、槲皮素(8)、松柏醛(9)、芥子醛(10)、哈巴苷(11)、8-O-乙酰哈巴苷(12)、芹菜素-7-O-β-D-吡喃葡萄糖苷(13)、异荭草苷(14)、山奈酚-3-O-β-D-葡萄糖苷(15)、芹菜素-6,8-二-C-β-D-吡喃葡萄糖苷(16)。结论:化合物1~16均为首次从该植物中分离得到,提示毛麝香具有一定的开发价值。Objective:To study the chemical constituents of ethyl acetate site of ethanol extract of Adenosma glutinosum(L.)Druce.Methods:The compounds are isolated and purified by column chromatography on silica gel and dextran gel,together with recrystallization,and the structure of each monomer compound is identified by spectroscopic means,physicochemical properties and literature.Results:Sixteen compounds are isolated of the ethyl acetate phase of ethanol extract of Adenosma glutinosum.It identified as 7-carbonyl-β-sitosterol(1),eugenic acid(2),lupeol(3),methyl p-hydroxycinnamate(4),geniposidic acid(5),luteolin(6),apigenin(7),quercetin(8),coniferyl aldehyde(9),sinapic aldehyde(10),harpagide(11),8-O-acetylharpagide(12),apigenin-7-O-β-D-glucopyranoside(13),isoorientin(14),kaempferol-3-O-β-D-glucopyranoside(15)and vicenin-2(16).Conclusion:Compounds 1~16 are isolated from Adenosma glutinosum for the first time,which suggests that Adenosma glutinosum has certain development value.

关 键 词：毛麝香 化学成分 核磁共振 

分 类 号：R282.6[医药卫生—中药学] O657.61[医药卫生—中医学]