尿流动力学检查参数与前列腺增生患者发生膀胱出口梗阻严重程度相关性分析  

Correlation of urodynamic parameters with severity of bladder outlet obstruction in patients with benign prostatic hyperplasia

作　　者：王付胜 王向阳[2] 徐国良 Wang Fus-heng;Wang Xiang-yang;Xu Guo-liang(Department of Urology,Changzheng People's Hospital,Shangqiu 476100,Henan,China;Department of Urology,Henan People's Hospital,Zhengzhou 450000,China;Department of Urology,The First Affiliated Hospital of Henan University,Zhengzhou 450000,China)

机构地区：[1]商丘市长征人民医院泌尿外科,河南商丘476100 [2]河南省人民医院泌尿外科,河南郑州450000 [3]河南大学第一附属医院泌尿外科,河南郑州450000

出　　处：《四川生理科学杂志》2023年第7期1159-1161,1275,共4页Sichuan Journal of Physiological Sciences

摘　　要：目的:探讨尿流动力学检查参数最大尿流率(Qura of maximum,Qmax)、残余尿量(Postvoid residual volume,PVR)、膀胱最大储尿量(Volume cystometric capacity,VMCC)与拟行膀胱造瘘术及经尿道前列腺电切术(Transurethral resection of the prostate,TURP)的前列腺增生患者发生膀胱出口梗阻(Bladder outlet obstruction,BOO)严重程度的相关性。方法:选取2019年8月~2021年6月于我院就诊的158例拟行膀胱造瘘术及TURP术的前列腺增生患者作为研究对象,所有患者均接受经膀胱造瘘术及尿流动力学检查,根据是否发生BOO分为BOO发生组(n=124)和BOO未发生组(n=34)。比较BOO发生组、BOO未发生组,以及BOO发生组中不同梗阻程度患者尿流动力学检查参数(Qmax、PVR、VMCC),分析Qmax、PVR、VMCC与前列腺增生患者发生BOO梗阻严重程度的相关性,并比较BOO不同预后患者的Qmax、PVR、VMCC。结果:BOO发生组Qmax、VMCC水平低于BOO未发生组,PVR水平高于BOO未发生组(P<0.05);BOO发生组不同严重程度患者的Qmax、VMCC水平比较:轻度梗阻>中度梗阻>重度梗阻(P<0.05);PVR水平比较:轻度梗阻<中度梗阻<重度梗阻(P<0.05)。Qmax、VMCC水平与是否发生BOO,及梗阻严重程度呈负相关(P<0.05),PVR水平与是否发生BOO,及梗阻严重程度呈正相关(P<0.05)。结论:尿流动力学检查参数Qmax、PVR、VMCC与行膀胱造瘘术的前列腺增生患者是否发生BOO及梗阻严重程度密切相关,临床可通过检测患者Qmax、PVR、VMCC水平,辅助临床判断BOO严重程度,为临床制定相应的治疗方案提供依据。Objective:To investigate the correlation of the urodynamic parameters,the qura of maximum(Qmax),postvoid residual volume(PVR),and volume cystometric capacity(VMCC)wit the severity of bladder outlet obstruction(BOO)in patients with benign prostatic hyperplasia who are planning to undergo cystostomy and transurethral resection of the prostate(TURP).Methods:A total of 158 patients with BPH who were scheduled to undergo cystostomy and TURP from August 2019 to June 2021 in our hospital were selected as the study subjects.All patients received cystostomy and urodynamic examination.They were divided into BOO occurrence group(n=124)and BOO non occurrence group(n=34)according to whether BOO occurred.The urodynamic parameters(Qmax,PVR,VMCC)were compared in patients with different degrees of obstruction in the BOO occurrence group,the BOO non occurrence group,and the BOO occurrence group.The correlation of Qmax,PVR,VMCC with the severity of BOO obstruction in patients with benign prostatic hyperplasia were analyzed,and the Qmax,PVR,VMCC were compared in patients with different prognosis of BOO.Results:The levels of Qmax and VMCC in the BOO group were lower than those in the BOO non occurrence group,and the PVR level was higher than that in the BOO non occurrence group(P<0.05);the levels of Qmax and VMCC comparison in patients with different severity in BOO group:mild obstruction>moderate obstruction>severe obstruction(P<0.05);the level of PVR comparison:mild obstruction<moderate obstruction<severe obstruction(P<0.05).The levels of Qmax and VMCC were negatively correlated with the occurrence of BOO and the severity of obstruction(P<0.05),while the level of PVR was positively correlated with the occurrence of BOO and the severity of obstruction(P<0.05).Conclusion:The urodynamic parameters Qmax,PVR,VMCC are closely related to the severity of BOO and obstruction in patients with BPH undergoing cystostomy.The clinical diagnosis of BOO severity can be assisted by the detection of Qmax,PVR,VMCC levels in patients with BPH undergoi

关 键 词：前列腺增生 膀胱出口梗阻 膀胱造瘘术 尿流动力学 

分 类 号：R697.3[医药卫生—泌尿科学]