“筋骨并重”视阈下鸢尾素对肌骨衰减的异病同治作用  

Exploring Effects of Irisin on Musculoskeletal Decay Based on Equal Emphasis on Sinews and Bones and Same Treatment for Different Diseases Theories

作　　者：刘晏东 邓强[2] 李中锋[2] 彭冉东 王雨榕 杨镇源[2] 郭铁峰[2] 罗林钊 LIU Yan-dong;DENG Qiang;LI Zhong-feng;PENG Ran-dong;WANG Yu-rong;YANG Zhen-yuan;GUO Tie-feng;LUO Lin-zhao(Clinical College of Traditional Chinese Medicine,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;Spinal Disease Diagnosis and Treatment Center,Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China)

机构地区：[1]甘肃中医药大学中医临床学院,甘肃兰州730000 [2]甘肃省中医院脊柱疾病诊疗中心,甘肃兰州730050

出　　处：《南京中医药大学学报》2023年第7期613-617,共5页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：中央财政转移支付地方项目(20210200111);国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2015039);兰州市科技计划项目(2022-3-30)。

摘　　要：骨骼和骨骼肌通过多种渠道相互串扰,共同组成机体最大的生物运动组织——肌肉骨骼系统。鸢尾素是一种由运动介导的激素样肌因子,具有同时调节肌再生和骨稳态的双重功能。基于“筋骨并重”及“异病同治”理论,从中西医两个维度出发,深入探析鸢尾素对肌肉及骨骼衰减病变的双重治疗作用,以期为肌骨共病的基础研究和临床防治提供新导向。Skeleton and skeletal muscle cross talk with each other through various channels,and together form the largest biological movement tissue of the body,the musculoskeletal system.Irisin is a kind of hormone-like muscle factor mediated by exercise,which has dual functions of simultaneously regulating muscle regeneration and bone homeostasis.Based on the theories of"equal emphasis on sinews and bones"and"same treatment for different diseases",this study explores the dual therapeutic effects of irisin on musculoskeletal decay lesions from the perspectives of traditional Chinese medicine and Western medicine,in order to provide new directions for basic research and clinical prevention and treatment of muscle and bone comorbidities.

关 键 词：筋骨并重 异病同治 鸢尾素 肌肉 骨骼 肌骨衰减 

分 类 号：R274.9[医药卫生—中西医结合]