Feasibility study of laser-driven neutron sources for pharmaceutical applications  

作　　者：Takato Mori Akifumi Yogo Yasunobu Arikawa Takehito Hayakawa Seyed R.Mirfayzi Zechen Lan Tianyun Wei Yuki Abe Mitsuo Nakai Kunioki Mima Hiroaki Nishimura Shinsuke Fujioka Ryosuke Kodama 

机构地区：[1]Institute of Laser Engineering,Osaka University,Suita,Japan [2]National Institutes for Quantum Science and Technology,Tokai,Japan [3]Tokamak Energy Ltd.,Abingdon,UK [4]Graduate School of Engineering,Osaka University,Suita,Japan [5]Fukui University of Technology,Fukui,Japan

出　　处：《High Power Laser Science and Engineering》2023年第2期37-43,共7页高功率激光科学与工程（英文版）

基　　金：This work was supported by the JSPS Bilateral Program(Grant No.JSPSBP120209922);JSPS KAKENHI(Grant Nos.JP22H02007 and JP22H01239).

摘　　要：We predict the production yield of a medical radioisotope^(67)Cu using^(67)Zn(n,p)^(67)Cu and ^(68)Zn(n,pn)^(67)Cu reactions with fast neutrons provided from laser-driven neutron sources.The neutrons were generated by the p+9Be and d+9Be reactions with high-energy ions accelerated by laser–plasma interaction.We evaluated the yield to be(3.3±0.5)×10^(5) atoms for^(67)Cu,corresponding to a radioactivity of 1.0±0.2 Bq,for a Zn foil sample with a single laser shot.Using a simulation with this result,we estimated^(67)Cu production with a high-frequency laser.The result suggests that it is possible to generate^(67)Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.

关 键 词：laser ion acceleration laser-driven neutron source medical radioisotope 

分 类 号：TN249[电子电信—物理电子学] R318[医药卫生—生物医学工程]