基于类石墨烯二维材料的光学生物传感  

Optical Biosensors Based on Graphene-Like Two-Dimensional Materials

作　　者：张家辉 王秀翃 Zhang Jiahui;Wang Xiuhong(Beijing Engineering Research Center of Laser Technology,Key Laboratory of Tran-Scale Laser Manufacturing Technology,Ministry of Education,Faculty of Materials and Manufacturing,Beijing University of Technology,Beijing 100124,China;Institute of Laser Engineering,Faculty of Materials and Manufacturing,Beijing University of Technology,Beijing 100124,China)

机构地区：[1]北京市激光应用技术工程技术研究中心,跨尺度激光成型制造技术教育部重点实验室,北京工业大学材料与制造学部,北京100124 [2]北京工业大学材料与制造学部激光工程研究院,北京100124

出　　处：《激光与光电子学进展》2023年第11期222-234,共13页Laser & Optoelectronics Progress

基　　金：国家自然科学基金(92053116,62035002)。

摘　　要：二维材料在许多方面相较于常规材料的优异性能,引发了研究人员对于二维材料的广泛关注。目前二维材料已经成为了各个领域内的研究热点,被广泛应用于生物医学、电子、光电子和催化等诸多方面。本文主要就二维材料在生物医学领域内的光学传感应用做了总结与讨论。主要论述了二维材料的产生和发展、优缺点,基于二维材料的光学生物传感器类型、原理及其制造方法,以及这些传感器在单细胞、RNA、蛋白质分子高灵敏探测技术上的一些成果,并结合这些成果简要分析了利用二维材料的实验方案相较于传统方法的一些优势。最后对二维材料的发展现状做了简要总结,并对其未来发展作出了展望。Due to the excellent performance of two-dimensional materials compared with conventional materials in many aspects,researchers have paid extensive attention to two-dimensional materials.At present,two-dimensional materials have become a research hotspot in various fields,and are widely used in biomedicine,electronics,optoelectronics and catalysis.This paper mainly summarizes and discusses the application of two-dimensional materials in optical sensing in the biomedical field.This paper mainly discusses the generation and development of two-dimensional materials,the advantages and disadvantages of two-dimensional materials and the types,principles and manufacturing methods of optical biosensors based on two-dimensional materials,as well as some achievements of these sensors in single-cell,RNA,protein molecule highly sensitive detection technology,and combines these results to briefly analyze some advantages of experimental schemes using two-dimensional materials compared with traditional methods.Finally,the development status of two-dimensional materials is briefly summarized,and their future development is prospected.

关 键 词：二维材料 光学生物传感 表面等离子体共振 荧光淬灭 表面增强拉曼散射 

分 类 号：TB383.1[一般工业技术—材料科学与工程] TP212.3[自动化与计算机技术—检测技术与自动化装置]