二氧化氯对微生物的杀灭机制研究进展  

Research progress on the mechanism of chlorine dioxide kilin microorganisms

作　　者：朱石荻 刘义明[1] 王玉凤 徐飞[1] 陈孝杰 李秀波[1] ZHU Shidi;LIU Yiming;WANG Yufeng;XU Fei;CHEN Xiaojie;LI Xiubo(Feed Research Institute/Key Laboratory of Antimicrobial Resistance Survellance of Animal-Derived Bacteria,Ministry of Agriculture and Rural Affairs/National Benchmark Laboratory for Drugs in Feed,Chinese Academy of Agricultural Sciences,Beijing 100086,China)

机构地区：[1]中国农业科学院饲料研究所/农业农村部动物源细菌耐药性监测重点实验室/国家饲料中药物基准实验室,北京100086

出　　处：《黑龙江畜牧兽医》2023年第14期33-36,共4页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家重点研发计划项目(2021YFD1800700);中国农业科学院创新工程项目(CAAS-FRI-06)。

摘　　要：二氧化氯消毒剂是国际上公认的高效灭菌消毒剂,对微生物有较强的杀灭作用,具有广谱、强力、快速、持久等特性,广泛应用于医疗卫生、食品加工、畜舍消毒、牧场天然饮用水处理等领域。但目前关于二氧化氯对微生物的灭活机制尚未完全明确。文章通过综述二氧化氯对细菌氨基酸、细胞结构、DNA分子及对病毒蛋白衣壳、遗传物质的作用阐明二氧化氯对微生物的杀灭机制,旨在为二氧化氯消毒剂的应用提供更加科学和可靠的依据,从而促进二氧化氯消毒剂产品的改进。Chlorine dioxide disinfectant is internationally recognized as an efficient sterilization disinfectant,which has a strong killing effect on microorganisms.It has broad spectrum,strong,fast and long lasting characteristics,and is widely used in medical and health care,food processing,livestock house disinfection,natural drinking water in pastures treatment and other fields.However,the inactivation mechanism of chlorine dioxide on microorganisms is not completely clear.This study reviewed the mechanism of chlorine dioxide on amino acid,cell structure,DNA molecule of bacteria,protein capsid and genetic material of viral to clarify the killing mechanism of chlorine dioxide on microorganisms,aiming to provide more scientific and reliable basis for the application of chlorine dioxide disinfectant and promote the improvement of chlorine dioxide disinfectant products.

关 键 词：二氧化氯 消毒剂 细菌 病毒 灭活机制 

分 类 号：Q93[生物学—微生物学]