Dysglycemia and arrhythmias  

作　　者：Dong-Kun Sun Nan Zhang Ying Liu Jiu-Chun Qiu Gary Tse Guang-Ping Li Leonardo Roever Tong Liu 

机构地区：[1]Department of Cardiology,Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease,Tianjin Institute of Cardiology,Second Hospital of Tianjin Medical University,Tianjin 300211,China [2]Kent and Medway Medical School,Kent CT27NT,Canterbury,United Kingdom [3]School of Nursing and Health Studies,Metropolitan University,Hong Kong 999077,China [4]Department of Clinical Research,Federal University of Uberlândia,Uberlândia,38400384,MG,Brazil

出　　处：《World Journal of Diabetes》2023年第8期1163-1177,共15页世界糖尿病杂志（英文版）（电子版）

基　　金：the National Natural Science Foundation of China,No.81970270,No.81570298,and No.81270245;Tianjin Key Medical Discipline(Specialty)Construction Project,No.TJYXZDXK-029A.

摘　　要：Disorders in glucose metabolism can be divided into three separate but interrelated domains,namely hyperglycemia,hypoglycemia,and glycemic variability.Intensive glycemic control in patients with diabetes might increase the risk of hypoglycemic incidents and glucose fluctuations.These three dysglycemic states occur not only amongst patients with diabetes,but are frequently present in other clinical settings,such as during critically ill.A growing body of evidence has focused on the relationships between these dysglycemic domains with cardiac arrhythmias,including supraventricular arrhythmias(primarily atrial fibrillation),ventricular arrhythmias(malignant ventricular arrhythmias and QT interval prolongation),and bradyarrhythmias(bradycardia and heart block).Different mechanisms by which these dysglycemic states might provoke cardiac arrhythmias have been identified in experimental studies.A customized glycemic control strategy to minimize the risk of hyperglycemia,hypoglycemia and glucose variability is of the utmost importance in order to mitigate the risk of cardiac arrhythmias.

关 键 词：DYSGLYCEMIA HYPERGLYCEMIA HYPOGLYCEMIA Glucose variability Cardiac arrhythmia 

分 类 号：R541.7[医药卫生—心血管疾病]