Brucellosis presenting with pancytopenia and hearing loss:A case report  

作　　者：Xing Chen Feng-Bo Yang Jian-Ying Liang 

机构地区：[1]Department of Infection,Nanchong Central Hospital,Nanchong 637000,Sichuan Province,China [2]Department of Otolaryngology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2023年第21期5187-5192,共6页世界临床病例杂志

摘　　要：BACKGROUND Brucellosis is one of the most common zoonotic infectious diseases in the world,with approximately 500000 new cases of human brucellosis diagnosed each year.Brucellosis can simulate various multi-system diseases,presenting atypical symptoms.Very few brucellosis cases with pancytopenia accompanied by a severe hearing loss have been reported.In the literature review,we could find only one similar case reported in the past.Moreover,this disease is easily misdiagnosed as a blood system disease leading to delayed treatment.Thus,it is important to improve clinicians'awareness of this disease.CASE SUMMARY A 64-year-old woman presented with dizziness and fatigue,accompanied by pancytopenia and severe hearing loss.Brucella melitensis was identified on blood culture.Anti-infective therapy with rifampicin(900 mg/d)and doxycycline(100 mg twice a day)was prescribed for 4 mo along with ceftriaxone 2 g/d for 1 mo.The patient showed a good response to antibiotic therapy.Her blood counts returned to normal followed by significant improvement in hearing.CONCLUSION Brucellosis should be considered in the differential diagnosis of patients presenting with pancytopenia and hearing loss.

关 键 词：BRUCELLOSIS PANCYTOPENIA Hearing loss NEUROBRUCELLOSIS Case report 

分 类 号：R516.7[医药卫生—内科学]