保留自主呼吸麻醉胸腔镜手术对原发性手汗症患者临床疗效、炎症因子的影响  

The impact of thoracoscopic surgery with anesthesia keeping spontaneous breathing on clinical efficacy and inflammatory factors of patients with primary palmar hyperhidrosis

作　　者：陈秀科[1] 李东涛[1] 张福维[1] 梁友君[2] 林宏彩[1] CHEN Xiuke;LI Dongtao;ZHANG Fuwei;LIANG Youjun;LIN Hongcai(Department of Cardiothoracic Surgery,the First People’s Hospital of Qinzhou,Guangxi,Qinzhou 535000,China;Department of Anesthesiology,the First People’s Hospital of Qinzhou,Guangxi,Qinzhou 535000,China)

机构地区：[1]广西壮族自治区钦州市第一人民医院胸心外科,广西钦州535000 [2]广西壮族自治区钦州市第一人民医院麻醉科,广西钦州535000

出　　处：《中国医药科学》2023年第14期106-109,共4页China Medicine And Pharmacy

基　　金：广西壮族自治区钦州市科学研究与技术开发计划项目(2021402)。

摘　　要：目的探讨保留自主呼吸麻醉方式在胸腔镜手术治疗原发性手汗症患者的应用效果。方法选取钦州市第一人民医院胸心外科2020年12月至2022年11月行胸腔镜手术治疗手汗症患者共40例。采用随机数表法分为观察组和对照组,每组各20例。观察组麻醉方式为保留自主呼吸的喉罩通气;对照组采取单腔气管插管肺通气。比较两组患者的术前麻醉诱导时间、手术时间、住院时间,并分析比较两组患者在麻醉前、手术结束72 h的炎症因子[白介素-6(IL-6)、C反应蛋白(CRP)]及并发症发生率。结果与对照组比较,观察组的术前麻醉诱导时间、住院时间较短(P<0.05),但两组手术时间比较,差异无统计学意义(P>0.05),麻醉前两组患者的炎症因子比较,差异无统计学意义(P>0.05),而手术结束72 h两组患者的IL-6和CRP均显著低于麻醉前,且观察组的IL-6和CRP指标均低于对照组(P<0.05),观察组的并发症总发生率低于对照组(P<0.05)。结论保留自主呼吸麻醉方式在胸腔镜手术治疗原发性手汗症患者中疗效显著,并可降低机体的炎症反应。Objective To explore the application effect of spontaneous breathing in the treatment of primary palmar hyperhidrosis by thoracoscopic surgery.Methods A total of 40 patients who underwent thoracoscopic surgery for palmar hyperhidrosis from December 2020 to November 2022 in the Department of Cardiothoracic Surgery of the First People’s Hospital of Qinzhou were selected.These patients were randomly divided into the observation group and the control group using a random number table method,with 20 cases in each group.The anesthesia method for the observation group is laryngeal mask ventilation that preserves spontaneous breathing;The control group received single lumen tracheal intubation for lung ventilation.The preoperative anesthesia induction time,surgical time,and hospitalization time were compared between the two groups,and the inflammatory factors(interleukin-6[IL-6],C-reactive protein[CRP])and complication rates of the two groups of patients before anesthesia and 72 hours after surgery were analyzed and compared.Results Compared with the control group,the observation group had shorter preoperative anesthesia induction time and hospitalization time(P<0.05),but there was no statistically significant difference in surgical time between the two groups(P>0.05).There was no significant difference in inflammatory indicators between the two groups before anesthesia(P>0.05).However,72 hours after surgery,the IL-6 and CRP levels of the two groups of patients were significantly lower than before anesthesia,and the IL-6 and CRP levels of the observation group were significantly lower than those of the control group(P<0.05),The total complication rate in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Anesthesia keeping spontaneous breathing is significantly effective in the treatment of primary palmar hyperhidrosis in patients undergoing thoracoscopic surgery,which can reduce the inflammatory response of the body.

关 键 词：自主呼吸 胸腔镜手术 原发性手汗症 临床疗效 炎症因子 

分 类 号：R655[医药卫生—外科学]