军队疗养体检人员甲状腺功能减退情况及与血糖血脂关系调查分析  

Investigation and analysis of the correlation of thyroid function with blood glucose and blood lipids in personnels undergoing military convalescent physical examination

作　　者：邓宗奎 罗文秀 林华玲 曹诚 DENG Zong-kui;LUO Wen-xiu;LIN Hua-ling;CAO Cheng

机构地区：[1]联勤保障部队桂林康复疗养中心健康管理部,广西桂林541003

出　　处：《中国疗养医学》2023年第9期930-933,共4页Chinese Journal of Convalescent Medicine

基　　金：军事医学课题基金(2016G01)。

摘　　要：目的 调查分析军队疗养体检人员甲状腺功能减退(简称甲减)患病情况及其与血糖、血脂的关系。方法 选取2016年1月至2019年12月在桂林康复疗养中心疗养体检的疗养员2 616例,进行甲状腺功能及生化检测,将检出的232例甲减患者(分临床甲减组及亚临床甲减组)作为病例组,并选取同时期军队疗养体检的232例甲状腺功能正常者作为对照组,比较病例组与对照组间甲状腺激素[促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)]及血糖(GLU)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDL-C)等指标的差异,并分析甲减患者甲状腺激素水平与血糖、血脂的相关性。结果 本研究对象2 616例,甲减总检出率为8.87%,其中女性(12.57%)显著高于男性(7.37%),亚临床甲减(7.91%)显著高于临床甲减(0.96%),≥65岁的甲减人群(15.02%)显著高于<65岁甲减人群(8.15%),差异均有统计学意义(P<0.05);甲减组、临床甲减组和亚临床甲减组的TSH、GLU、TC、TG水平均高于对照组,FT3及FT4水平均低于对照组,差异均有统计学意义(P<0.05);本研究甲减人群TSH及FT4水平与TC及TG均呈显著正相关(P<0.05)、FT3与GLU及TG呈显著正相关(P<0.05)。结论 军队疗养体检甲减患者甲状腺激素水平与血糖、血脂存在不同程度的相关性,临床上应积极矫治甲减症。Objective To investigate the prevalence of hypothyroidism in personnels undergoing military convalescent physical examination,and to identify its correlation with blood glucose and blood lipids.Methods A total of 2616 personnels undergoing military convalescent physical examination in Guilin Convalescent and Rehabilitation Center from January 2016 to December 2019 were recruited.They were examined for thyroid function and biochemical testing.A total of 232 personnels detected with hypothyroidism were included in case group,and they were further subgrouped into clinical hypothyroidism group and subclinical hypothyroidism group.During the same period,232 personnels undergoing military convalescent physical examination with the normal thyroid function were selected as control group.Thyroid hormones,including thyroid-stimulating hormone(TSH),free triiodothyronine(FT3),and free thyroxine(FT4),as well as blood glucose(GlU),total cholesterol(TC),triglyceride(TG),high density lipoprotein(HDL-C)and low density lipoprotein(LDL-C)between the case group and the control group were compared.The correlation of thyroid hormones with blood glucose and blood lipids in hypothyroidism patients was analyzed.Results The total detection rate of hypothyroidism was 8.87%among 2616 subjects,which,in female patients was significantly higher than that of male patients(12.57%VS 7.37%,P<0.05).The detection rate of subclinical hypothyroidism was significantly higher than that of clinical hypothyroidism(7.91%VS 0.96%,P<0.05).The detection rate of hypothyroidism in personnels older than 65 years of age was significantly higher than those of younger than 65 years(15.02%VS 8.15%,P<0.05).TSH,GlU,TC and TG levels were higher in clinical hypothyroidism group and subclinical hypothyroidism group than in control group,while FT3 and FT4 levels were significantly lower(P<0.05).TSH and FT4 levels in hypothyroidism patients were positively correlated with TC and TG levels(P<0.05),and FT3 level was positively correlated with GlU and TG levels(P<0.05).Conclu

关 键 词：疗养体检 甲状腺激素 高血糖 高脂血症 相关性 

分 类 号：R581.2[医药卫生—内分泌]