阿司匹林结合除颤监护仪治疗急性心肌梗死的临床效果  

Clinical effect of aspirin combined with defibrillation monitor in the treatment of acute myocardial infarction

作　　者：邸睿宁 赵江龙 丁亮 DI Ruining;ZHAO Jianglong;DING Liang(Xi'an Chang'an Hospital,Xi'an 710016;Baoji High-tech Hospital,Baoji 721006,China)

机构地区：[1]西安长安医院,陕西西安710016 [2]宝鸡高新医院,陕西宝鸡721006

出　　处：《临床医学研究与实践》2023年第22期73-76,共4页Clinical Research and Practice

基　　金：陕西省宝鸡市卫生健康委员会2019年度科研计划立项课题(No.2019-65)。

摘　　要：目的分析阿司匹林结合除颤监护仪治疗急性心肌梗死的临床效果。方法选择2019年1月至12月收治的82例急性心肌梗死患者作为研究对象,将其随机分为除颤组(41例,常规除颤监护仪治疗)和联合组(41例,阿司匹林结合除颤监护仪治疗)。比较两组的治疗效果。结果联合组住院期间的死亡、缺血发作、再发心肌梗死、消化道出血发生率均显著低于除颤组(P<0.05)。联合组的心肺复苏时间、自主循环恢复时间、冠脉再通时间及住院时长均显著短于除颤组(P<0.05)。治疗后,联合组的血流储备分数(FFR)、平均血流速度(Vm)显著高于除颤组,微循环抵抗指数(IMR)、阻力指数(RI)显著低于除颤组(P<0.05)。治疗后,联合组的脑利钠肽(BNP)、心肌肌钙蛋白T(cTnT)、可溶性ST2蛋白(sST2)及D-二聚体(D-D)水平低于除颤组,凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)长于除颤组(P<0.05)。结论阿司匹林结合除颤监护仪治疗急性心肌梗死患者的临床效果显著,可快速恢复心肺功能,值得临床应用。Objective To analyze the clinical effect of aspirin combined with defibrillation monitor in the treatment of acute myocardial infarction.Methods A total of 82 patients with acute myocardial infarction admitted from January to December 2019 were selected as the study objects and randomly divided into defibrillation group(41 cases,treated with conventional defibrillation monitor)and combined group(41 cases,treated with aspirin combined with defibrillation monitor).The therapeutic effects of the two groups were compared.Results The incidence of death,ischemic attack,recurrent myocardial infarction and gastrointestinal bleeding during hospitalization in the combined group were significantly lower than those in the defibrillation group(P<0.05).The cardiopulmonary resuscitation time,spontaneous circulation recovery time,coronary recanalization time and hospitalization time in the combined group were significantly shorter than those in the defibrillation group(P<0.05).After treatment,the fractional flow reserve(FFR)and mean blood flow velocity(Vm)of the combined group was significantly higher than that of the defibrillation group,and the index of microcirculation resistance(IMR)and resistent index(RI)were significantly lower than those of the defibrillation group(P<0.05).After treatment,the levels of brain natriuretic peptide(BNP),cardiac troponin T(cTnT),soluble ST2 protein(sST2)and D-dimer(D-D)in the combined group were lower than those in the defibrillation group,and the prothrombin time(PT),activated partial thromboplastin time(APTT)were longer than those in the defibrillation group(P<0.05).Conclusion Aspirin combined with defibrillation monitor has a significant clinical effect in the treatment of patients with acute myocardial infarction.It can quickly restore cardiopulmonary function and is worthy of clinical application.

关 键 词：急性心肌梗死 冠状动脉粥样硬化 阿司匹林 除颤监护仪 

分 类 号：R542.22[医药卫生—心血管疾病]