Harvesting the fruits of the first stage of the Primate Genome Project  

作　　者：Yuan-Ting Guo Yong Shao Xupeng Bi Bao-Lin Zhang Hong Wu Yang Zhou Ming-Li Li Li Yu Guojie Zhang Dong-Dong Wu Xiao-Guang Qi 

机构地区：[1]College of Life Sciences,Northwest University,Xi’an,Shaanxi 710069,China [2]State Key Laboratory of Genetic Resources and Evolution,Kunming Natural History Museum of Zoology,Kunming Institute of Zoology,Chinese Academy of Sciences,Kunming,Yunnan 650201,China [3]Centre for Evolutionary&Organismal Biology,and Women’s Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang 310058,China [4]State Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan,School of Life Sciences,Yunnan University,Kunming,Yunnan 650091,China [5]BGI-Shenzhen,Shenzhen,Guangdong 518083,China [6]Department of Neurology,First Affiliated Hospital of Zhengzhou University,Zhengzhou University,Zhengzhou,Henan 450052,China [7]Liangzhu Laboratory,Zhejiang University Medical Center,Hangzhou,Zhejiang 311121,China [8]Villum Centre for Biodiversity Genomics,Section for Ecology and Evolution,Department of Biology,University of Copenhagen,Copenhagen DK-2100,Denmark [9]Center for Excellence in Animal Evolution and Genetics,Chinese Academy of Sciences,Kunming,Yunnan 650201,China [10]National Resource Center for Non-Human Primates,Kunming Primate Research Center,and National Research Facility for Phenotypic&Genetic Analysis of Model Animals(Primate Facility),Kunming Institute of Zoology,Chinese Academy of Sciences,Kunming,Yunnan 650107,China [11]KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases,Kunming Institute of Zoology,Chinese Academy of Sciences,Kunming,Yunnan 650204,China

出　　处：《Zoological Research》2023年第4期725-728,共4页动物学研究（英文）

摘　　要：Primates are highly successful mammals with significant morphological,behavioral,and physiological diversity.Studying the genomes of non-human primates,as the closest relative of humans,can provide insights into human evolution,genetic structure,and potential drug targets relevant to human health,thus making important contributions to medical research.Additionally,primate genome research can support ecological balance and resource conservation and promote sustainable development and human well-being.Despite the existence of more than 500 primate species belonging to 80 genera and 16 families worldwide,with new species still being discovered in recent years(Fan et al.,2017;Khanal et al.,2021;Roos et al.,2020),genome sequencing efforts have been limited to a relatively small number of species from only 22 genera(Ensembl v103).Notably,approximately 72%of primate genera remain unsequenced,leading to significant knowledge gaps in our understanding of their evolutionary history.This situation presents considerable challenges for the development,utilization,and protection of primate genetic resources.It is for these compelling reasons that we initiated the Primate Genome Project(PGP)(Wu et al.,2022).

关 键 词：initiated SPITE GENERA 

分 类 号：Q953[生物学—动物学]