口腔扁平苔藓患者焦虑抑郁状况与艾森克人格特质分析  

Analysis of anxiety and depression condition and Eysenck personality traits in oral lichen planuspatients

作　　者：林小洁[1,3] 周以欣 马化兵 曾启新 牙祖科[1,3] 梅国城 苏娟秀[1] 陈智佳 陶人川 Lin Xiaojie;Zhou Yixin;Ma Huabing;Zeng Qixin;Ya Zuke;Mei Guocheng;Su Juanxiu;Chen Zhijia;Tao Renchuan(College&Hospital of Stomatology,Guangxi Medical University,Nanning 530021,China;Beihai People’s Hospital,Beihai 536000,China;Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases,Nanning 530021,China)

机构地区：[1]广西医科大学口腔医学院/附属口腔医院,南宁530021 [2]北海市人民医院,北海536000 [3]广西壮族自治区卫生健康委员会口腔感染性疾病防治重点实验室,南宁530021

出　　处：《广西医科大学学报》2023年第7期1140-1145,共6页Journal of Guangxi Medical University

基　　金：国家自然科学基金资助项目(No.81771073);广西卫生和计划生育委员会课题资助项目(No.Z2016454)。

摘　　要：目的:分析口腔扁平苔藓(OLP)患者疾病状态与焦虑、抑郁症状水平和人格特质的相关性,为该疾病的防治提供参考依据。方法:于2017年2月至2018年3月采用焦虑自评量表(SAS)、抑郁自评量表(SDS)及艾森克人格问卷(EPQ),对34例糜烂型口腔扁平苔藓患者(E-OLP)、46例非糜烂型口腔扁平苔藓患者(NE-OLP)及52例健康志愿者进行测评,结合患者疾病状态,分析OLP疾病状况与焦虑、抑郁症状水平及人格某些特质的相关关系。结果:E-OLP组焦虑阳性率(47.06%)、抑郁阳性率(52.94%),均高于健康对照组(均P<0.05)。通过logistic回归分析,OLP患者焦虑、抑郁阳性与否均与半定量网纹—糜烂—溃疡(REU)评分(OR=1.809,95%CI:1.072~3.054;OR=1.663,95%CI:1.068~2.589)、N维度评分(OR=1.233,95%CI:1.086~1.400;OR=1.211,95%CI:1.068~1.374)有关(均P<0.05)。通过多重线性回归分析,SAS、SDS分值均与病程、N维度评分有关(均P<0.05)。OLP患者的多血质构成比小于健康对照组(P=0.009)。结论:口腔扁平苔藓患者的人格特征与焦虑/抑郁症状水平存在一定相关性。OLP患者情绪不稳定,具有较为内向的人格特征。随着REU评分及艾森克神经质分数的增加,OLP患者更容易出现焦虑、抑郁状态,尤其是糜烂型OLP患者。Objective:To analyze the correlation between disease status of oral lichen planus(OLP)patients and the levels of anxiety,depression and personality traits,and to provide reference for the prevention and treatment of this disease.Methods:From February 2017 to March 2018,34 patients with erosive oral lichen planus(E-OLP),46 patients with non-erosive oral lichen planus(NE-OLP)and 52 healthy volunteers were evaluated to ana-lyze the relationship between disease status of OLP and the levels of anxiety,depression and certain personality traits by Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS)and Eysenck Personality Questionnaire(EPQ).Results:The positive rates of anxiety(47.06%)and depression(52.94%)in the E-OLP group were higher than those in the healthy control group(both P<0.05).Logistic regression analysis showed that whether OLP patients were positive for anxiety and depression or not was correlated with semi-quantitative reticulate-erosive-ulcerative(REU)scores(OR=1.809,95%CI:1.072-3.054;OR=1.663,95%CI:1.068-2.589)and N-dimension scores(OR=1.233,95%CI:1.086-1.400;OR=1.211,95%CI:1.068-1.374)(all P<0.05).Multiple linear regression analysis showed that SAS scores and SDS scores were correlated with disease duration and N-dimension scores(all P<0.05).OLP patients had a lower composition ratio of polycythemia than those in the healthy control group(P=0.009).Conclusion:The personality traits of OLP patients are correlated with the level of anxiety/depression symptoms.OLP patients are emotionally unstable and tend to have introverted personality traits.With the increase of REU scores and Eysenck neuroticism scores,OLP patients are more prone to anxiety and depression,especially erosive OLP patients.

关 键 词：口腔扁平苔藓 抑郁 焦虑 人格特质 

分 类 号：R781.59[医药卫生—口腔医学]