真菌球性上颌窦炎发病相关因素的分析  

Analysis of factors related to fungal ball maxillary sinusitis

作　　者：宋壮壮 葛思辰 江涛[1] 许亚佳[1] 蒋成义[1] Song Zhuangzhuang;Ge Sichen;Jiang Tao;Xu Yajia;Jiang Chengyi(Department of Otorhinolaryngology Head and Neck Surgery,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China)

机构地区：[1]蚌埠医学院第一附属医院耳鼻咽喉头颈外科,蚌埠233004

出　　处：《中华解剖与临床杂志》2023年第7期476-479,共4页Chinese Journal of Anatomy and Clinics

摘　　要：目的探讨真菌球性上颌窦炎(FBMS)发病的相关因素。方法回顾性病例对照研究。纳入2019年9月—2021年12月蚌埠医学院第一附属医院耳鼻咽喉头颅外科行手术治疗并经术后病理确诊为单侧FBMS的患者75例,其中男30例、女45例,年龄27~83(54.3±13.0)岁。选取同期75例慢性上颌窦炎患者作为对照组,其中男49例、女26例,年龄15~83(43.6±17.0)岁。对2组患者年龄、性别、吸烟、饮酒、高血压、哮喘、上颌牙手术史、鼻腔鼻窦解剖变异类型等进行单因素分析,将其中P<0.05的因素进一步进行多因素logistic回归分析。结果单因素分析结果显示,年龄、性别、高血压、糖尿病、上颌牙手术史、泡状中鼻甲、反张中鼻甲、钩突偏曲是FBMS发病的影响因素,差异均有统计学意义(P值均<0.05)。多因素logistic回归分析显示:≥45岁[比值比(OR)=4.889,95%可信区间(CI)2.025~11.800]、女性(OR=2.311,95%CI 1.016~5.256)、上颌牙手术史(OR=4.382,95%CI 1.216~15.783)、泡状中鼻甲(OR=3.404,95%CI 1.182~9.806)、反张中鼻甲(OR=9.080,95%CI 2.013~40.958)是FBMS发病的独立危险因素。结论年龄(≥45岁)、女性、合并有上颌牙手术史、中鼻甲异常是FBMS的独立危险因素,早期临床诊断时应重视以上因素。Objective To investigate factors related to fungal ball maxillary sinusitis.Methods A retrospective analysis was performed on 75 patients with fungal ball maxillary sinusitis.The patients included 30 males and 45 females,aged 27-83(54.3±13.0)years,who underwent surgical treatment in the Department of Otolaryngology Head and Neck Surgery,the First Affiliated Hospital of Bengbu Medical College from September 2019 to December 2021 and confirmed via postoperative pathology.In addition,75 patients with chronic maxillary sinusitis,including 49 males and 26 females,aged 15-83(43.6±17.0)years,who were treated in our department during the same period,were selected.Patients with chronic maxillary sinusitis were chosen as the control.The clinical data(age,gender,smoking habit,drinking habit,hypertension,asthma,and maxillary dental surgery history)of the patients and the anatomical variations of their nasal cavity and sinuses(nasal septum deviation,vesicular middle turbinate,inverted middle turbinate,Haller air chamber,unate process hypertrophy,unate process deviation,and sieve bubble hyper gasification)were used in the univariate analysis.Factors with P<0.05 were further analyzed via multivariate logistic regression.Results The univariate analysis showed that age,sex,hypertension,diabetes,maxillary dental surgery history,vesicular middle turbinate,retraction of middle turbinate,and unate process deviation were the influencing factors for the onset of fungal ball maxillary sinusitis.The difference was statistically significant(all P values<0.05).The multivariate logistic regression analysis showed that≥45 years old(odds ratio[OR]=4.889,95%confidence interval[CI]2.025~11.800),female(OR=2.311,95%CI 1.016-5.256),maxillary tooth operation history(OR=4.382,95%CI 1.216-15.783),inverted middle turbinate(0R=3.404,95%CI 1.182-9.806),and vesicular middle turbinate(0R=9.080,95%CI 2.013-40.958)were independent risk factors for fungal ball maxillary sinusitis.Conclusion Age(≥45 years old),female,combined maxillary dental surgery hi

关 键 词：鼻窦炎 真菌球性上颌窦炎 解剖变异 上颌牙 相关因素 

分 类 号：R765.42[医药卫生—耳鼻咽喉科]