中药穴位贴敷、穴位艾灸联合肺康复训练在慢性阻塞性肺疾病患者中的应用  

Application of Chinese Medicine Acupoint Application,Acupoint Moxibustion Combined with Lung Rehabilitation Training in Patients with Chronic Obstructive Pulmonary Disease

作　　者：饶丽仙 黄晨娟 黄彩珠 曾文君 RAO Lixian;HUANG Chenjuan;HUANG Caizhu;ZENG Wenjun(Shaowu Municipal Hospital,Fujian Province,Shaowu 354000,China;不详)

机构地区：[1]福建省邵武市立医院,福建邵武354000

出　　处：《中国医学创新》2023年第21期129-133,共5页Medical Innovation of China

摘　　要：目的:探讨中药穴位贴敷、穴位艾灸联合肺康复训练干预慢性阻塞性肺疾病的临床效果及对炎症因子及免疫功能的影响。方法:回顾分析邵武市立医院2020年1月—2022年6月收治的82例符合入组标准的慢性阻塞性肺疾病患者的临床资料,按干预方式不同分为对照组41例和观察组41例,两组患者均进行常规药物治疗,对照组患者给予肺康复训练干预,观察组患者在对照组的基础上再给予中药穴位贴敷联合穴位艾灸干预,两组均干预30 d。干预前及干预30 d结束时进行中医症状积分评判,采用呼吸困难量表(mMRC)评价呼吸困难改善情况,采用慢性阻塞性肺疾病评估测试表(CAT)评价患者生活质量改善情况,采用酶联免疫吸附试验法测定血清炎症因子(肿瘤坏死因子-α、白介素-6、超敏C反应蛋白),采用流式细胞仪测定T淋巴细胞亚群。结果:观察组干预30 d结束时咳嗽、咳痰、肺啰音、喘息评分均明显低于干预前及对照组干预后,差异均有统计学意义(P<0.05)。观察组干预30 d结束时m MRC评分、CAT评分均明显低于干预前及对照组干预后,差异均有统计学意义(P<0.05)。观察组干预30 d结束时肿瘤坏死因子-α、白介素-6、超敏C反应蛋白均明显低于干预前及对照组干预后,差异均有统计学意义(P<0.05)。观察组干预30 d结束时CD4^(+)、CD4^(+)/CD8^(+)均明显高于干预前及对照组干预后,差异均有统计学意义(P<0.05)。结论:中药穴位贴敷、穴位艾灸联合肺康复训练干预慢性阻塞性肺疾病能够有效减轻炎症反应,进而改善临床症状,缓解呼吸困难,同时有助于提高机体免疫功能,降低疾病复发,有效提高患者生活质量。Objective:To investigate the clinical effect of acupoint application of traditional Chinese medicine,acupoint moxibustion combined with lung rehabilitation training on chronic obstructive pulmonary disease and its influence on inflammatory factors and immune function.Method:Retrospective analysis was made on the clinical data of 82 patients with chronic obstructive pulmonary disease admitted to Shaowu Municipal Hospital from January 2020 to June 2022.They were divided into control group(41 cases)and observation group(41 cases)according to different intervention methods.Both groups received conventional drug treatment,while the control group received lung rehabilitation training intervention.The observation group was additionally given Chinese medicine acupoint application combined with acupoint moxibustion intervention on the basis of control group,intervention for 30 d in both groups.TCM symptom score evaluation was performed before intervention and at the end of 30 days of intervention,dyspnea scale(mMRC)was used to evaluate the improvement of dyspnea,chronic obstructive pulmonary disease assessment test(CAT)was used to evaluate the improvement of quality of life of the patients,serum inflammatory factors(tumor necrosis factor-α,interleukin-6,hypersensitive C reactive protein)were determined by enzyme-linked immunosorbent assay,T lymphocyte subsets were determined by flow cytometry.Result:At the end of 30 days of intervention,the scores of cough,sputum,pulmonary rales and wheezing in the observation group were significantly lower than those before intervention and those in the control group after intervention,with statistical significance(P<0.05).At the end of 30 days of intervention,mMRC score and CAT score in the observation group were significantly lower than those before intervention and those in the control group after intervention,with statistical significance(P<0.05).At the end of 30 days of intervention,tumor necrosis factor-α,interleukin-6 and hypersensitive C reactive protein in the observation grou

关 键 词：慢性阻塞性肺疾病 穴位贴敷 穴位艾灸 肺康复训练 

分 类 号：R248.1[医药卫生—中医临床基础]