经尿道绿激光汽化术治疗高危前列腺增生症的效果和安全性分析  

Analysis of the Efficacy and Safety of Transurethral Green Laser Vaporization in the Treatment of High-risk Benign Prostatic Hyperplasia

作　　者：郑增斌 余良智 邹根贵 邱俊 吴文博 ZHENG Zengbin;YU Liangzhi;ZOU Gengui;QIU Jun;WU Wenbo(Shangrao People's Hospital,Jiangxi Province,Shangrao 334100,China;不详)

机构地区：[1]江西省上饶市人民医院,江西上饶334100

出　　处：《中国医学创新》2023年第22期27-31,共5页Medical Innovation of China

基　　金：江西省卫生健康委科技计划项目(202312282)。

摘　　要：目的:探讨经尿道绿激光汽化术(PVP)治疗高危前列腺增生症(BPH)的效果和安全性。方法:选取上饶市人民医院2020年3月—2022年4月收治的90例高危BPH患者,随机分为两组,分别为对照组(n=45)和观察组(n=45),对照组行经尿道前列腺电切术,观察组行经尿道PVP。比较两组围手术期相关指标,治疗前、治疗后3个月的相关指标,包括最大尿流率(Qmax)、生活质量量表(QOL)评分、国际前列腺症状评分(IPSS)、国际勃起功能指数评分问卷表-5(IIEF-5)分值和应激反应,以及治疗后3个月并发症发生情况。结果:观察组手术时长、膀胱冲洗时间、留置尿管时间及住院时间均短于对照组,术中出血量少于对照组,差异均有统计学意义(P<0.05)。治疗后3个月,观察组的Qmax及IIEF-5分值均高于对照组,QOL评分及IPSS评分均低于对照组,差异均有统计学意义(P<0.05);观察组皮质醇(Cor)、去甲肾上腺素(NE)、肾上腺素(E)及空腹血糖(FBG)均低于对照组,差异均有统计学意义(P<0.05);观察组并发症发生率为13.33%,低于对照组的33.33%,差异有统计学意义(P<0.05)。结论:经尿道PVP能够有效治疗高危BPH患者,其不仅并发症发生率低,安全性较高,且术后恢复快。Objebtive:To investigate the efficacy and safety of transurethral green laser photoselective vaporization of the prostate(PVP)in the treatment of high-risk benign prostatic hyperplasia(BPH).Method:A total of 90 patients with high-risk BPH from March 2020 to April 2022 in Shangrao People's Hospital were randomly divided into the control group(n=45)and the observation group(n=45).The control group was underwent transurethral resection of prostate,and the observation group was underwent transurethral PVP.The perioperative indexes,the relevant indicators before treatment and three months after treatment included the maximum urinary flow rate(Qmax),quality of life(QOL)score,the international prostate symptom score(IPSS),the international index of erectile function score question-5(IIEF-5)score,the stress response,and the incidence of complications three months after treatment were compared between the two groups.Result:The operation time,bladder irrigation time,indwelling catheter time and hospitalization time of the observation group were shorter than those of the control group,intraoperative blood loss was less than that of the control group,the differences were statistically significant(P<0.05).Three months after treatment,the Qmax and IIEF-5 score of the observation group were higher than those of the control group,and the QOL score and IPSS score were lower than those of the control group,the differences were statistically significant(P<0.05);cortisol(Cor),norepinephrine(NE),epinephrine(E)and fasting blood glucose(FBG)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05);the complication rate of the observation group was 13.33%,which was lower than 33.33%of the control group,the difference was statistically significant(P<0.05).Conclusion:Transurethral PVP can effectively treat high-risk BPH patients,which not only has a low incidence of complications with high safety,but also has rapid postoperative recovery.

关 键 词：经尿道绿激光汽化术 高危前列腺增生 尿道前列腺电切术 

分 类 号：R699.8[医药卫生—泌尿科学]