Chiral inorganic nanomaterials:Harnessing chirality-dependent interactions with living entities for biomedical applications  

作　　者：Qi Gao Lili Tan Zhihao Wen Daidi Fan Junfeng Hui Peng-peng Wang 

机构地区：[1]Shaanxi Key Laboratory of Degradable Biomedical Materials,Shaanxi R&D Center of Biomaterials and Fermentation Engineering,School of Chemical Engineering,Northwest University,Xi’an 710069,China [2]State Key Laboratory for Mechanical Behavior of Materials,Shaanxi International Research Center for Soft Matter,School of Materials Science and Engineering,Xi’an Jiaotong University,Xi’an 710049,China

出　　处：《Nano Research》2023年第8期11107-11124,共18页纳米研究（英文版）

基　　金：The authors acknowledge the support from the National Natural Science Foundation of China(Nos.22001201,22075224,and 22078265);the Science and Technology Agency of Shaanxi Province(No.2022KWZ-21).

摘　　要：Chirality is an intriguing and fundamental property of natural matter,which is especially crucial in supporting the processes of living systems.The selective interactions between natural chiral compounds are widespread at all levels in living entities and play a vital role in biochemical reactions.The cutting-edge advancements in synthetic chiral inorganic nanostructures have led to significant progress in their applications within biological systems.These developments have unraveled chirality-dependent interactions at the nanoscale and molecular scale,providing a better understanding of intricate process of chiral selection in biological systems and demonstrating the potential of chiral inorganic nanostructures for life science applications.Herein,we summarize recent progress in understanding the chirality origin of inorganic chiral nanoparticles and the development of wet-chemical synthesis.We also discuss the captivating interaction between chiral inorganic nanostructures and biological entities at various scales.Finally,we discuss the challenges and potential of functional chiral nanomaterials for future biomedical and bioengineering applications,offering design ideas and a forecast for their future impact.

关 键 词：chiral inorganic nanomaterials living system chirality-dependent interaction bioengineering application 

分 类 号：O62[理学—有机化学]