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作 者:郭立玮 王永香 钟文蔚 李鹏 曾浩然 GUO Li-wei;WANG Yong-xiang;ZHONG Wen-wei;LI Peng;ZENG Hao-ran(Guangzhou Bio-Green Technology Co.,Ltd.,Guangzhou 511455,China;Yangtze River Pharmaceutical(Group)Co.,Ltd.,Taizhou 225321,China;Nanjing Hailing Traditional Chinese Medicine Pharmaceutical Technology Research Co.,Ltd.,Nanjing 218085,China;School of Chinese Medicinal Resource,Guangdong Pharmaceutical University,Guangzhou 510006,China)
机构地区:[1]广州百奥格林生物科技有限公司,广东广州511455 [2]江苏扬子江药业集团有限公司,江苏南京225321 [3]南京海陵中药制药工艺技术研究有限公司,江苏南京218085 [4]广东药科大学中药资源学院,广东广州510006
出 处:《中草药》2023年第13期4385-4394,共10页Chinese Traditional and Herbal Drugs
摘 要:膜分离技术对中药制药工艺的创新来源于多学科交叉研究。中药膜分离科技是材料化学工程学科先进的分离科学技术与中药制药学跨学科结合的产物,其技术原理是对传统中药制药分离各主要操作单元技术原理的创新。逐一论述了中药制药分离过程各主要操作单元的本质特征、技术原理及膜科学技术对中药制药分离过程工程原理的创新作用。并指出基于膜“绿色制造”技术的中药制药分离过程“低碳流程再造”的工程原理与工艺基础实现了膜科学技术的多尺度效应、“膜一体化”系统与中药制药分离工艺流程的全面兼容;而中药行业膜技术标准零的突破则为该“低碳流程再造”的规模应用及可复制提供了坚实的基础,展示出巨大的市场应用前景。The innovation of membrane separation technology to traditional Chinese medicine(TCM)pharmaceutical technology comes from multi-disciplinary research.TCM membrane separation technology is the product of the interdisciplinary combination of advanced separation science and technology of material chemical engineering and TCM pharmaceutical science,and its technical principle is the innovation of the technical principle of the main operating units of TCM pharmaceutical separation.The essential characteristics,technical principles of the main operation units and the innovative effect of membrane science and technology on the engineering principles of TCM pharmaceutical separation process were discussed one by one.The engineering principle and technological basis of“low carbon process re-engineering”based on membrane“green manufacturing”technology realize the full compatibility of the multi-scale effect of membrane science and technology,“membrane integration”system and the separation process of traditional Chinese medicine.The breakthrough of membrane technology standard zero in the Chinese medicine industry provides a solid foundation for the scale application and replicability of the“low-carbon process re-engineering”,and shows a huge market application prospect.
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