中医药“脑肠同调”防治功能性脑肠疾病多学科交叉研究思路探讨  

Multidisciplinary Research Thinking on the Prevention and Treatment of Functional Brain-Intestinal Diseases with "Brain-Gut Coordinating" of Chinese Medicine

作　　者：方霜霜 蒋天媛 曹增 独思静 魏玮[1] FANG Shuang-shuang;JIANG Tian-yuan;CAO Zeng;DU Si-jing;WEI Wei(Department of Gastroenterology,Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102;Graduate School of Beijing University of Chinese Medicine,Beijing 100029)

机构地区：[1]中国中医科学院望京医院脾胃病科,北京100102 [2]北京中医药大学研究生院,北京100029

出　　处：《中国中西医结合杂志》2023年第7期863-867,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金资助项目(No.81820108033);国家中医药管理局中医药行业科研专项项目(No.201507001-09)。

摘　　要：中医药“脑肠同调”法对调节胃肠微生态、改善胃肠动力、降低内脏高敏感、缓解焦虑抑郁状态等具有重叠作用,契合脑肠共病的患病模式,对脑肠互动异常疾病治疗具有优势。笔者系统梳理了脑肠互动异常脑肠疾病的研究现状与现存的关键问题,包括基础研究存在技术瓶颈、客观诊断标准缺乏、治疗方法有限与疾病管理困难等。并针对关键问题探讨“脑肠同调”思路指导下的多学科交叉攻关研究思路,以期为今后的研究提供参考与借鉴。The "brain-gut coordinating" method of Chinese medicine has overlapping effects on different mechanisms including regulating gastrointestinal microecology,improving gastrointestinal motility,reducing visceral hypersensitivity,relieving anxiety and depression,etc.,which fits the prevalence pattern of cerebroenteric comorbidities.It has advantages in the treatment of diseases with abnormal brain-gut interaction.The authors systematically sorted out the latest research progress and found the existing key problems of brain-gut diseases with abnormal brain-gut interaction,including technical bottlenecks in basic research,lack of objective diagnostic standards,limited treatment methods,and difficulties in disease management.And aiming at the key issues,discuss the multidisciplinary interdisciplinary research ideas under the guidance of the "brain-gut coherence" idea,hoping to provide reference and reference for future research.

关 键 词：脑肠同调 多学科交叉 功能性胃肠病 功能性脑病 

分 类 号：R277.7[医药卫生—中医学]