儿童嗜酸性膀胱炎的临床病理及CT分析  

Clinical pathology and CT analysis of eosinophilic cystitis in children

作　　者：魏伟安 陈卫坚[2] 易婷 金科[1] WEI Wei'an;CHEN Weijian;YI Ting;JIN Ke(Department of Radiology,Hunan Children's Hospital,Changsha 410007,China;Department of Pathology,Hunan Children's Hospital,Changsha 410007,China)

机构地区：[1]湖南省儿童医院放射科,湖南长沙410007 [2]湖南省儿童医院病理科,湖南长沙410007

出　　处：《实用放射学杂志》2023年第7期1155-1158,共4页Journal of Practical Radiology

摘　　要：目的 探讨儿童嗜酸性膀胱炎(EC)的CT影像特征及临床病理.方法 回顾性分析经临床病理确诊的10例EC患儿的临床资料及泌尿系CT影像表现.所有患儿均进行平扫、增强及延时扫描,重点观察膀胱壁形态、厚度、强化和延时特征表现.结果 8例患儿临床上表现为尿频、尿急,部分合并尿痛,2例表现为排尿困难.实验室检查显示大部分患儿的外周血嗜酸性粒细胞比值不同程度增高,病理提示黏膜、黏膜下层及肌层数量不一的嗜酸性粒细胞等炎性细胞浸润并可见水肿.影像上CT显示膀胱容积缩小,外周多发增粗血管,膀胱壁增厚呈进行性强化,局限性2例,弥漫性8例.膀胱内漂浮着完整的黏膜线,轻度强化,黏膜下宽窄不一的低密度水肿带.结论 儿童EC的主要CT表现为膀胱壁增厚、新生血管、黏膜完整及低密度水肿带,同时结合临床实验室及病史可作出初步诊断.Objective To explore the CT imaging characteristics and clinical pathology of eosinophilic cystitis(EC)in children.Methods The clinical data and urinary CT imaging findings of 10 children with EC diagnosed by clinicopathology were analyzed retrospectively.All children underwent plain,enhanced and delayed scan,focusing on the morphology,thickness,enhancement and delayed characteristics of the bladder wall.Results The clinical manifestations of 8 cases were frequent urination and urgent urination,some of them were complicated with pain,and the other 2 cases showed dysuria.Laboratory examination showed the ratio of eosinophils in peripheral blood of most children increased in variable degrees,and pathology indicated infiltration of inflammatory cells such as variable numbers of eosinophils and edema in the mucosa,submucosa and muscularis.CT imaging showed reduced bladder volume,peripheral multiple thickened vessels,and progressive enhancement of thickened bladder wall,which was localized in 2 cases and diffuse in 8 cases.The bladder was floated with an intact mucousal line,slightly enhanced,and a broad submucosal band of hypodense edema.Conclusion The main CT findings of EC in children are thickened bladder wall,neovascularization,intact mucosa and hypodense edematous bands,which,together with clinical laboratory and medical history,can lead to the initial diagnosis.

关 键 词：嗜酸性膀胱炎 儿童 计算机体层成像 

分 类 号：R694.3[医药卫生—泌尿科学] R814.42[医药卫生—外科学]