气阴两虚型2型糖尿病患者血糖波动与人体成分分析指标相关性的研究  

Correlation between Blood Glucose Fluctuation and Body Composition Analysis Indicators in Patients with T2DM of Qi and Yin Deficiency

作　　者：陆立群 徐隽斐[1] LU Liqun;XU Junfei(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学附属曙光医院,上海201203

出　　处：《中医药学报》2023年第8期66-70,共5页Acta Chinese Medicine and Pharmacology

基　　金：上海市科委项目(17401970400);上海市临床重点专科(shslczdzk05401);上海市中医临床重点实验室(20DZ2272200)。

摘　　要：目的:探究气阴两虚型2型糖尿病患者血糖波动性与人体成分分析的关系,为临床诊疗提供新的思路。方法:采用回顾性研究的方法,选取2020年9月—2021年9月在上海中医药大学附属曙光医院内分泌科住院的气阴两虚型2型糖尿病患者共169例。通过双变量相关性分析研究血糖波动与人体成分分析相关指标的相关性,包括评价血糖波动指标[目标范围内时间(TIR)、24 h平均血糖波动幅度(MAGE)、最大血糖波动幅度(LAGE)、24 h平均血糖值(MBG)、日间血糖平均绝对差(MODD)、血糖变异系数(CV)、血糖标准差(SDBG)、糖化血红蛋白(HbA1c)],评价人体成分分析指标[相对骨骼肌质量指数(RASM)、总肌肉含量(TLM),体质量指数(BMI),Android区域脂肪百分比、Gynoid区域脂肪百分比,A/G及体脂率]。结果:RASM与TIR呈显著正相关,与SDBG、MAGE、CV呈显著负相关。TLM与SDBG、CV呈显著负相关。Android区域脂肪百分比与SDBG、CV、HbA1c呈显著正相关。A/G与SDBG、MAGE、MODD、CV呈显著正相关。体脂率与LAGE、CV呈显著正相关。结论:气阴两虚型2型糖尿病患者血糖波动与人体成分分析指标间具有显著相关性,即骨骼肌含量越高、体脂率越低,则气阴两虚型2型糖尿病患者的血糖波动越平稳。Objective:To explore the relationship between blood glucose fluctuation and body composition analysis in patients with type 2 diabetes mellitus(T2DM)of Qi and Yin deficiency,thus to provide new ideas for clinical diagnosis and treatment of the disease.Methods:A retrospective study method was used to select a total of 169 patients with T2DM of Qi and Yin deficiency,who were hospitalized in the Department of Endocrinology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from September 2020 to September 2021.Bivariate correlation analysis was used to study the correlation between blood glucose fluctuation and related indicators of body composition analysis,including evaluating blood glucose fluctuation indicators(TIR,MAGE,LAGE,MBG,MODD,CV,SDBG HbA1c),and to evaluate body composition analysis indicators(RASM,TLM,BMI,fat percentage in Android area,fat percentage in Gynoid area,A/G and body fat rate).Results:RASM was significantly positively correlated with TIR and was significantly negatively correlated with SDBG,MAGE and CV.TLM was significantly negatively correlated with SDBG and CV.The percentage of fat in the Android region was significantly positively correlated with SDBG,CV,and HbA1c.A/G was significantly positively correlated with SDBG,MAGE,MODD and CV.Body fat percentage was significantly positively correlated with LAGE and CV.Conclusion:There is a significant correlation between blood sugar fluctuation in patients with T2DM of Qi and Yin deficiency and body composition analysis indicators,that is,the higher the skeletal muscle content and the lower the body fat rate are,the more stable the blood sugar fluctuation will be in patients with T2DM of Qi and Yin deficiency.

关 键 词：2型糖尿病 气阴两虚证 血糖波动 人体成分分析 

分 类 号：R255.4[医药卫生—中医内科学]