PDCA循环管理在卵胞浆内单精子注射技术质量控制中的应用  

Application of PDCA management in quality control of intracytoplasmic sperm injection technology

作　　者：鲜红 滕文顶 王芳 张攀 段霜 杨付桥 杜昊轩 XIAN Hong;TENG Wen-ding;WANG Fang;ZHANG Pan;DUAN Shuang;YANG Fu-qiao;DU Hao-xuan(Department of Reproduction and Infertility,the Affiliated Hospital,School of Medicine,UESTC,Chengdu Women’s and Children’s Central Hospital,Chengdu610091)

机构地区：[1]电子科技大学医学院附属医院成都市妇女儿童中心医院生殖健康与不孕症科,成都610091

出　　处：《生殖医学杂志》2023年第8期1185-1190,共6页Journal of Reproductive Medicine

摘　　要：目的分析PDCA循环管理方案对辅助生殖助孕治疗中卵胞浆内单精子注射(ICSI)技术临床效果的影响,并评估其临床应用价值。方法根据PDCA质量管理工具要求,分析成都市妇女儿童中心医院生殖中心ICSI质量现状,选定质量改进主题,分析影响ICSI质量相关因素,设立改进目标,确定要因,制定改进措施,对ICSI技术各质量环节进行持续改进,并根据PDCA循环管理结果建立ICSI助孕治疗实验室标准作业流程。对比分析2015年1月至2021年12月在本中心进行ICSI治疗的2057个周期的患者资料,比较PDCA管理前后ICSI各质量指标的变化。结果纳入的2057个ICSI周期中,女性平均年龄(33.55±5.94)岁,不孕年限(4.50±3.98)年。实施PDCA循环管理方案后,2016年1月至2021年12月在本生殖中心行ICSI治疗患者的实验室各关键质量指标均逐步提升并稳定在较高水平;与2015年相比,2021年的受精率(88.03%vs.78.98%)、卵裂率(98.65%vs.94.73%)、优胚率(38.20%vs.24.09%)及临床妊娠率(52.50%vs.36.05%)均显著提高(P<0.001)。结论采用PDCA管理方法对ICSI技术进行质量管理,能显著提升并稳定ICSI助孕效果。Objective:To analyze the impact of PDCA management on the clinical efficacy of intracytoplasmic sperm injection(ICSI)technology in assisted reproductive therapy,and evaluate its clinical application value.Methods:According to the requirements of PDCA quality management tool,the study analyzed the current situation of ICSI quality in the Reproductive Center of Chengdu Women’s and Children’s Central Hospital,selected the theme of quality improvement,analyzed the factors affecting ICSI quality,set improvement goals,determined the main factors,developed improvement measures,continuously improved the quality of ICSI technology and established the standard operating process of ICSI fertility treatment laboratory according to the results of PDCA management.The data of 2057 patients who underwent ICSI treatment at our center from January 2015 to December 2021 were compared and analyzed,and the changes in various quality indicators of ICSI before and after implementing PDCA management were compared.Results:Among the 2057 ICSI cycles included,the average age of women was(33.55±5.94)years and the duration of infertility was(4.50±3.98)years.After implementing PDCA management,the key quality indicators of ICSI in our hospital from January 2016 to December 2021 were gradually improved and stabilized.Compared with 2015,the fertilization rate(88.03%vs.78.98%),cleavage rate(98.65%vs.94.73%),high-qualified embryo rate(38.20%vs.24.09%)and pregnancy rate(52.50%vs 36.05%)were significant improved in 2021(P<0.001).Conclusions:PDCA management method can significantly improve and stabilize the quality of ICSI technology.

关 键 词：辅助生殖技术 PDCA 卵胞浆内单精子注射 临床妊娠率 

分 类 号：R711.6[医药卫生—妇产科学]