定喘汤加减联合下肢运动训练治疗卒中后相关性肺炎的临床效果  

Clinical effect of modified Dingchuan Decoction combined with lower limb exercise training on post-stroke related pneumonia

作　　者：蔡艺贞 周嘉澄 CAI Yizhen;ZHOU Jiacheng(Department of Encephalopathy and Respiratory Medicine,Baiyun District,Guangdong Second Hospital of Traditional Chinese Medicine(Guangdong Institute of Traditional Chinese Medicine Engineering and Technology),Guangdong Province,Guangzhou 510095,China)

机构地区：[1]广东省第二中医院(广东省中医药工程技术研究院)白云院区脑病呼吸科,广东广州510095

出　　处：《中国当代医药》2023年第22期7-10,32,共5页China Modern Medicine

基　　金：广东省中医药局科研项目(20212007)。

摘　　要：目的观察定喘汤加减联合下肢运动训练治疗卒中后相关性肺炎(SAP)的临床效果。方法选取2021年10月1日至2022年8月10日广东省第二中医院白云院区住院部收治的60例SAP患者作为研究对象,按照随机数字表法分为观察组和对照组,每组各30例。对照组采用西医常规药物治疗,观察组在对照组基础上采用定喘汤加减联合下肢运动训练治疗方法,比较两组患者干预2周后的疗效、C反应蛋白(CRP),治疗前后临床肺部感染评分(CPIS)、中医症状分级量化评分、日常生活能力评分(ADL)、呼吸困难程度评分、美国国立卫生研究院卒中量表(NIHSS)评分。结果观察组的有效率(63.33%)高于对照组(46.67%),差异有统计学意义(P<0.05)。观察组治疗后的CRP为(10.23±0.22)mg/dl,低于对照组的(13.12±0.09)mg/dl,差异有统计学意义(P<0.05)。观察组治疗后的CPIS得分为(3.23±0.14)分,低于对照组的(5.64±0.82)分,差异有统计学意义(P<0.05)。观察组治疗后的中医症状分级量化评分为(8.12±0.51)分,低于对照组的(12.05±0.44)分,差异有统计学意义(P<0.05)。观察组治疗后的ADL得分为(28.63±0.21)分,低于对照组的(36.52±0.35)分,差异有统计学意义(P<0.05)。观察组治疗后的呼吸困难程度评分为(2.20±0.11)分,低于对照组的(3.10±0.57)分,差异有统计学意义(P<0.05)。观察组治疗后的NIHSS得分为(20.04±0.37)分,低于对照组的(28.21±0.85)分,差异有统计学意义(P<0.05)。结论定喘汤加减联合下肢运动训练治疗SAP的效果较好,优于单纯的西医常规治疗,可明显降低炎症水平,有效改善临床症状,提高患者生存质量。Objective To observe the clinical effect of modified Dingchuan Decoction combined with lower limb exercise training on post-stroke related pneumonia(SAP).Methods Sixty patients with SAP admitted to the inpatient department of Baiyun District,Guangdong Second Hospital of Traditional Chinese Medicine from October 1,2021 to August 10,2022 were selected as the study objects,and were divided into observation group and control group according to random number table method,with 30 cases in each group.The control group was treated with conventional western medicine,the observation group was treated with modified Dingchuan Decoction combined with lower limb exercise training on the basis of the control group.The therapeutic effect,C-reactive protein(CRP),clinical pulmonary infection score(CPIS)before and after treatment,traditional Chinese medicine symptom grading score,daily living ability score(ADL),National Institutes of Health stroke scale(NIHSS)score of the two groups were compared after 2 weeks of intervention.Results The effective rate of observation group(63.33%)was higher than that of control group(46.67%),and the difference was statistically significant(P<0.05).After treatment,the CRP of observation group was(10.23±0.22)mg/dl,which was lower than that of control group([13.12±0.09]mg/dl),the difference was statistically significant(P<0.05).The CPIS score of the observation group after treatment was(3.23±0.14)points,lower than that of the control group([5.64±0.82]points),and the difference was statistically significant(P<0.05).After treatment,the traditional Chinese medicine symptom grading score of the observation group was(8.12±0.51)points,lower than that of the control group([12.05±0.44]points),and the difference was statistically significant(P<0.05).The ADL score of the observation group after treatment was(28.63±0.21)points lower than that of the control group(36.52±0.35)points,and the difference was statistically significant(P<0.05).The degree of dyspnea in the observation group was(2.20±0.11)points

关 键 词：定喘汤 双下肢运动训练 卒中 肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]