Visible Light-Driven Catalyst-Free Amination of Indoles Initiated by Electron Donor-Acceptor Complexes  

作　　者：Jiahong Sui Zhonglie Yang Shuangqiao Li Xueqin Chen Xiaobin Zhang Qing Shen Hezhong Jiang Jiahong Li 

机构地区：[1]School of Life Science and Engineering, Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, Southwest Jiaotong University, Chengdu, Sichuan, 610031 China [2]Department of Pharmacy, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital/Personalized Drug Therapy Key Laboratory of Sichuan Province, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072 China

出　　处：《Chinese Journal of Chemistry》2023年第12期1485-1490,共6页中国化学（英文版）

基　　金：financial support from the National Natural Science Foundation of China(Grant Nos.21901216 and 82074003,82174083);the Funds of Sichuan Science and Technology Program(23NSFSC0862,2021YFSY0041,2021YFH0064 and 2021ZHFP0032);the Opening subject under KF-202204 in the State Key Laboratory of Pharmaceutical Biotechnology,Nanjing University,China,the Fund of Science and Technology Agency of Chengdu(2019-YF09-00049-SN);the research project of the Administration of Traditional Chinese Medicine of Sichuan(2021MS110);the Open Project Program of Irradiation Preservation Technology Key Laboratory of Sichuan Province,Sichuan Institute of Atomic Energy(No.FZBC2020002);the Fundamental Research Funds for the Central Universities(2682020ZT85).

摘　　要：The visible light-driven C2 or C3 amination of indoles without any additives was initiated via electron donor-acceptor (EDA) complex formed by indole and N-aminopyridinium salt.This method was compatible with a wide range of substrates and could proceed smoothly without the addition of any photocatalysts,transition-metal catalysts,or bases.A variety of studies were carried out to examine the presence of EDA complex.

关 键 词：PHOTOCHEMISTRY AMINATION C-N bond formation Green chemistry N-HETEROCYCLES Donor-acceptor systems 

分 类 号：O62[理学—有机化学]