己酮可可碱治疗糖尿病足的效果观察  

Effect Observation of Pentoxifylline in Treatment of Diabetic Foot

作　　者：王娟 Wang Juan(Department of Endocrinology,Nanjing Qixia District Hospital,Nanjing 210046,Jiangsu Province,China)

机构地区：[1]南京市栖霞区医院内分泌科,江苏南京210046

出　　处：《中国社区医师》2023年第21期42-44,共3页Chinese Community Doctors

摘　　要：目的:探讨己酮可可碱治疗糖尿病足的效果。方法:选取2021年1月—2022年10月南京市栖霞区医院收治的糖尿病足患者60例作为研究对象,根据治疗方式的不同分为两组,各30例。对照组采用常规治疗,观察组在对照组基础应用己酮可可碱治疗。比较两组临床疗效、病足溃疡面面积、血浆黏度。结果:观察组治疗有效率高于对照组,差异有统计学意义(P<0.001)。治疗前,两组病足溃疡面积比较,差异无统计学意义(P>0.05);治疗后,两组病足溃疡面积均小于治疗前,且观察组小于对照组,差异有统计学意义(P<0.05)。治疗前,两组血浆黏度比较,差异无统计学意义(P>0.05);治疗后,两组血浆黏度均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论:在常规治疗的基础上,加用己酮可可碱治疗糖尿病足,可提高糖尿病足患者的治疗效果,缩小病足溃疡面面积,降低血浆黏度。Objective:To investigate the effect of pentoxifylline in the treatment of diabetic foot.Methods:A total of 60 diabetic foot patients admitted to Nanjing Qixia District Hospital from January 2021 to October 2022 were selected as the study subjects,and they were divided into two groups with 30 cases according to different treatment methods.The control group was given conventional treatment,and the observation group was given pentoxifylline treatment on the basis of the control group.The clinical efficacy,ulcer area of affected foot and plasma viscosity of the two groups were compared.Results:The effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.001).Before treatment,there was no significant difference in the ulcer area of affected foot between the two groups(P>0.05).After treatment,the ulcer area of affect foot in the two groups was smaller than that before treatment,and the observation group was smaller than the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the plasma viscosity between the two groups(P>0.05).After treatment,the plasma viscosity in the two groups was lower than that before treatment,and the observation group was lower than the control group,and the difference was statistically significant(P<0.05).Conclusion:On the basis of conventional treatment,the addition of pentoxifylline in treatment of diabetic foot can improve the treatment effect of diabetic foot patients,reduce the ulcer area of affected foot,and reduce plasma viscosity.

关 键 词：糖尿病病足 己酮可可碱 血浆黏度 溃疡面积 

分 类 号：R587.2[医药卫生—内分泌]