持续性胸段硬脊膜外麻醉在颅脑外伤性应激性溃疡治疗中的效果分析  

Effect analysis of continuous thoracic epidural anesthesia in the treatment of stress ulcer after craniocerebral injury

作　　者：苏金运 SU Jin-yun(Nan'an Hospital,Nan'an 362300,China)

机构地区：[1]南安市医院,362300

出　　处：《中国现代药物应用》2023年第14期93-95,共3页Chinese Journal of Modern Drug Application

摘　　要：目的研究持续性胸段硬脊膜外麻醉用于颅脑外伤性应激性溃疡患者的疗效。方法选取80例颅脑外伤性应激性溃疡患者开展随机对照研究,随机分为对照组和观察组,每组40例。对照组接受奥美拉唑治疗,观察组接受持续性胸段硬脊膜外麻醉治疗。比较两组临床疗效、各项治疗指标。结果观察组治疗总有效率95.00%高于对照组的72.50%,差异有统计学意义(P<0.05)。观察组止血时间(2.67±0.51)d、住院时间(5.67±1.34)d均短于对照组的(5.96±1.28)、(9.46±1.75)d,胃液pH值(5.82±0.78)高于对照组的(3.94±0.45),消化道出血量(433.76±109.83)ml低于对照组的(678.51±125.49)ml,差异有统计学意义(P<0.05)。结论持续性胸段硬脊膜外麻醉应用于颅脑外伤性应激性溃疡患者治疗中有助于提高治疗效果,缩短患者治疗时间,改善临床症状,应用价值良好。Objective To study the efficacy of continuous thoracic epidural anesthesia in the treatment of stress ulcer after craniocerebral injury.Methods A randomized controlled study was conducted on 80 patients with stress ulcer after craniocerebral injury,and they were randomly divided into control group and observation group,with 40 cases in each group.The control group was treated with omeprazole,and the observation group was treated with continuous thoracic epidural anesthesia.The clinical efficacy and therapeutic indexes of the two groups were compared.Results The total effective rate of 95.00%in the observation group was higher than that of 72.50%in the control group,and the difference was statistically significant(P<0.05).The hemostatic time of(2.67±0.51)d and hospital stay of(5.67±1.34)d in the observation group were shorter than those of(5.96±1.28)and(9.46±1.75)d in the control group;the gastric fluid pH of(5.82±0.78)in the observation group was higher than that of(3.94±0.45)in the control group;the amount of gastrointestinal bleeding of(433.76±109.83)ml in the observation group was lower than that of(678.51±125.49)ml in the control group;the differences were statistically significant(P<0.05).Conclusion The application of continuous thoracic epidural anesthesia in patients with stress ulcer after craniocerebral injury can improve the therapeutic effect,shorten the treatment time,improve clinical symptoms,and has good application value.

关 键 词：颅脑外伤性应激性溃疡 持续性胸段硬脊膜外麻醉 奥美拉唑 

分 类 号：R614[医药卫生—麻醉学]