改性PLA/ESO/HA材料用于3D打印医用塑料止血夹  

Modified PLA/ESO/HA Material Used for 3D Printing of a Medical Plastic Hemostatic Clip

作　　者：张志成 谢德明[1] ZHANG Zhicheng;XIE Deming(Department of Biomedical Engineering,Jinan University,Guangzhou 510630,China)

机构地区：[1]暨南大学生物医学工程系,广东广州510630

出　　处：《塑料工业》2023年第7期150-155,169,共7页China Plastics Industry

摘　　要：设计一款医用塑料止血夹,轮廓采用“V”型结构,调整塑性铰与扣锁部位。选取聚乳酸(PLA)为基体材料,添加环氧大豆油(ESO)与羟基磷灰石(HA)进行改性,制备PLA/ESO/HA复合材料并测试力学性能,通过有限元分析与3D打印止血夹对比PLA改性前后效果。结果表明,含3%HA的PLA/ESO/HA复合材料综合性能最佳,拉伸强度与弹性模量较PLA材料提高18.7%和降低34.6%。PLA/ESO/HA复合材料仿真止血夹应力分布均匀,塑性铰与扣锁部位最大应力较PLA材料仿真结果分别降低61.2%与32.7%。打印成型操作得PLA材料止血夹因断裂导致良品率低,而PLA/ESO/HA复合材料止血夹可实现良好闭合,结论与仿真结果相符,具备临床应用前景。A medical plastic hemostatic clip was designed with the shape of“V”structure,and the plastic hinge and buckle structure were adjusted.Poly(lactic acid)(PLA)was selected as the matrix material,epoxy soybean oil(ESO)and hydroxyapatite(HA)were added for modification,PLA/ESO/HA composite was prepared and its mechanical properties were tested.The effects of PLA modification before and after modification were compared by finite element analysis and 3D printing hemostatic clip.The results show that the PLA/ESO/HA composite with 3%HA has the best comprehensive properties,and the tensile strength and elastic modulus are 18.7%higher and 34.6%lower than PLA.The PLA/ESO/HA composite simulated stress distribution of the hemostatic clip is uniform,and the maximum stress of the plastic hinge and buckle is reduced by 61.2%and 32.7%,respectively,comparing with the simulation results of PLA material.The PLA hemostatic clip obtained from the printing operation has a low yield rate due to fracture,while the PLA/ESO/HA composite hemostatic clip can achieve good closure.This conclusion is consistent with the simulation results and has clinical application prospects.

关 键 词：聚乳酸 环氧大豆油 羟基磷灰石 有限元分析 3D打印 医用止血夹 

分 类 号：TQ321.2[化学工程—合成树脂塑料工业]