Liquid exfoliation of stanene as degradable nanoagents for NIR-II photothermal therapy  

作　　者：Xueqiao Li Weijian Li Zhaohua Miao Chenxi Lu Hongna Ma Yan Xu Deyan Gong Cheng-Yan Xu Zhengbao Zha 

机构地区：[1]School of Food and Biological Engineering,Hefei University of Technology,Hefei 230009,China [2]College of Nuclear Equipment and Nuclear Engineering,Yantai University,Yantai 264005,China [3]School of Materials Science and Engineering,Harbin Institute of Technology(Shenzhen),Shenzhen 518055,China [4]Shenzhen Bay Laboratory,Shenzhen 518052,China

出　　处：《Journal of Materials Science & Technology》2023年第17期186-198,共13页材料科学技术（英文版）

基　　金：financially supported by the National Natural Sci-ence Foundation of China(No.52071120);the University Synergy Innovation Program of Anhui Province(Nos.GXXT-2019-045 and GXXT-2020-063);the Open Foundation of Shenzhen Bay Lab-oratory(No.SZBL2019062801005).

摘　　要：Stanene,the two-dimensional form of elemental tin(Sn),is easily oxidized in the ambient environ-ment,significantly hindering its applications in biomedical fields.However,the degradation mechanism of stanene remains unclear.Herein,combined DFT calculations and proof-of-concept experiments were conducted to elucidate the underlying degradation mechanism of stanene.The results reveal that the degradation of stanene in an oxygenated water environment is a water-accelerated oxidation process.H_(2) O molecules could not only facilitate the electron transfer from stanene to O_(2) because of the polarization effect of H_(2) O,but also directly react with the defect sites of stanene due to enhanced absorption energy.Moreover,several protective strategies like alcohol protection were proposed to avoid or mitigate the oxidation of stanene for further applications.Finally,stanene was explored as the second near-infrared(NIR-II)photonic agents for ablation of 4T1 tumor,depicting a tumor-growth inhibition ratio up to 96.7%,much better than that of the first near-infrared(NIR-I)group(65.5%).This work reveals the degradation mechanism of stanene and demonstrates its biomedical applications in the NIR-II region.

关 键 词：Stanene Degradation mechanism DFT calculations Photothermal therapy NIR-II 

分 类 号：TB383.1[一般工业技术—材料科学与工程]