一氧化氮参数在儿童支气管哮喘中的临床应用价值  

Clinical value of nitric oxide parameters in children with bronchial asthma

作　　者：韦紫倩 依力木古丽·阿卜杜克热木 吴葆菁[1] Wei Ziqian;Yilimuguli Abudukeremu;Wu Baojing(Department of Pediatrics,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China)

机构地区：[1]中山大学孙逸仙纪念医院儿科,广州510120 [2]喀什地区第一人民医院儿科,喀什844000

出　　处：《新医学》2023年第8期549-553,共5页Journal of New Medicine

基　　金：广东省援疆农村科技(特派员)项目(KTPYJ20211010)。

摘　　要：呼出气一氧化氮(eNO)作为嗜酸性气道炎症的标志物,在哮喘的诊疗中应用广泛。口呼出气一氧化氮(FeNO)主要反映大气道炎症水平,通过建立肺动力学模型对其进行扩展分析,可以获得一氧化氮参数,有助于更好地了解呼吸道炎症水平。该文回顾近年相关研究,就一氧化氮参数在哮喘治疗中的临床应用价值做一综述,以期为哮喘的评估和管理研究增加新的维度。Exhaled nitric oxide(eNO),as a marker of eosinophilic inflammation in the airway,has been widely utilized in the diagnosis and treatment of asthma.The fractional concentration of exhaled NO(FeNO)mainly reflects the degree of airway inflammation.By establishing a pulmonary dynamic model for extended analysis,nitric oxide parameters can be obtained,which contribute to deepen the understanding of the degree of airway inflammation.In this article,recent studies were reviewed to summarize the clinical value of nitric oxide parameters in asthma,aiming to supplement a novel dimension for the evaluation and management of asthma.

关 键 词：呼出气一氧化氮 一氧化氮参数 哮喘 气道炎症 

分 类 号：R725.6[医药卫生—儿科]