现代分析技术在中药炮制化学研究中的应用  

Application of Modern Analytical Techniques in Processing Chemistry of Traditional Chinese Medicine

作　　者：朱雨洁 郭溶 高珣 沈金阳 李伟东[2] 禹志领[3] 蔡宝昌[2] 秦昆明 ZHU Yu-jie;GUO Rong;GAO Xun;SHEN Jin-yang;LI Wei-dong;YU Zhi-ling;CAI Bao-chang;QIN Kun-ming(School of Pharmacy,Jiangsu Ocean University,Lianyungang 222000,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China;School of Chinese Medicine,Hong Kong Baptist University,Hongkong,China)

机构地区：[1]江苏海洋大学药学院,江苏连云港222000 [2]南京中医药大学药学院,江苏南京210023 [3]香港浸会大学中医药学院,中国香港999077

出　　处：《分析测试学报》2023年第8期1056-1063,共8页Journal of Instrumental Analysis

基　　金：国家自然科学基金项目(81873004,81573603,81603297);江苏省高校自然科学研究重大项目(21KJA360005);江苏省中医药局科技项目(YB2020109)。

摘　　要：中药炮制是依据中医学理论基础、辨证用药的基本要求、药物自身特性而采取的制药工艺。中药炮制化学研究旨在阐明中药炮制过程中化学成分的变化及其规律,从而为阐明中药炮制机理奠定基础。当前以色谱-质谱联用技术为代表的现代分析技术已广泛应用于中药炮制化学研究,为揭示中药炮制过程中化学成分变化提供了有力手段,也为确保中药饮片质量安全和可控起到很大的推动作用。该文对多种现代分析技术在中药炮制化学研究中的应用现状进行了综述。Traditional Chinese medicine processing is a pharmaceutical technology which is adopted according to the theory of traditional Chinese medicine,the need of syndrome differentiation,the na-ture of medicinal materials.The research on processing chemistry of traditional Chinese medicine aims to clarify the changes of chemical constituents and their rules during the processing of traditional Chinese medicine,so as to lay a foundation for elucidating the processing mechanism of traditional Chinese medicine.Nowadays,modern analytical techniques represented by chromatography-mass spectrometry have been widely used in the research of Chinese medicine processing chemistry,which provides a powerful means to reveal the chemical composition changes of Chinese medicine process-ing,and also plays a great role in promoting the quality safety and control of Chinese medicine decoc-tion pieces.The application of several modern analytical techniques in processing chemistry of traditional Chinese medicine is reviewed in this paper,and its future development is also prospected.

关 键 词：现代分析技术 中药炮制 成分变化 

分 类 号：O657.63[理学—分析化学] R283[理学—化学]