28194例患者维生素D缺乏的患病率调查及危险因素分析  

Prevalence survey and analysis of risk factors for vitamin D deficiency among 28194 cases

作　　者：汪青[1] 钱胤华 黄昊强 徐锋[1] 陈勇[1] 彭志坚[1] WANG Qing;QIAN Yinhua;HUANG Haoqiang;XU Feng;CHEN Yong;PENG Zhijian(Osteoporosis Osteopathy Prevention and Treatment Center,Kunshan Traditional Chinese Medicine Hospital,Kunshan,Jiangsu 215300,China)

机构地区：[1]昆山市中医医院骨质疏松骨病防治中心,江苏昆山215300

出　　处：《重庆医学》2023年第15期2305-2309,2314,共6页Chongqing medicine

基　　金：江苏省老年健康科研项目(LK2021044);昆山市高层次医学人才引进项目(01201801);苏州市临床重点病种诊疗技术专项项目(LCZX202127)。

摘　　要：目的调查昆山地区医院门诊及住院患者维生素D缺乏的患病率,并探讨其相关危险因素。方法将28194例昆山市中医医院门诊及住院患者作为研究对象,其中男9259例,女18935例,对患者资料进行回顾性研究。结果28194例患者血清25羟维生素D水平为18(12,23)ng/mL,维生素D缺乏患病率为59.15%。二元logistic回归分析结果显示,住院[比值比(OR)=2.210,95%置信区间(95%CI):2.082~2.345,P<0.001]、冬季(OR=1.598,95%CI:1.481~1.724,P<0.001),女性(OR=2.042,95%CI:1.932~2.158,P<0.001)、低龄(OR=2.439,95%CI:2.104~2.829,P<0.001)是发生维生素D缺乏的危险因素。结论昆山地区医院门诊及住院患者维生素D缺乏比较普遍,尤其在冬春季住院的低年龄段女性患者,应进行维生素D缺乏的筛查。Objective To investigate the prevalence of vitamin D deficiency among outpatients and inpatients in hospitals in the Kunshan area,and explore the related risk factors.Methods A total of 28194 outpatients and inpatients were selected as the research subjects at Kunshan Hospital of Traditional Chinese Medicine.The sample included 9259 males and 18935 females.The patients’data was retrospectively studied.Results The serum^(2)5-hydroxyvitamin D level of 28194 patients was 18(12,23)ng/mL,and the prevalence of vitamin D deficiency was 59.15%.Binary logistic regression analysis showed that hospitalization(OR=2.210,95%CI:2.082-2.345,P<0.001),winter(OR=1.598,95%CI:1.481-1.724,P<0.001),female(OR=2.042,95%CI:1.932-2.158,P<0.001),and young age(OR=2.439,95%CI:2.104-2.829,P<0.001)were risk factors for vitamin D deficiency.Conclusion Vitamin D deficiency is prevalent among both outpatients and inpatients in hospitals in the Kunshan area,particularly among younger female patients who are hospitalized during the winter and spring seasons.Therefore,it is recommended that these patients be screened for vitamin D deficiency.

关 键 词：25羟维生素D 维生素D缺乏 季节 性别 年龄 

分 类 号：R681[医药卫生—骨科学]