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作 者:杨培慧 Yang Peihui(Department of Pharmacy,Ningguo Hospital of Traditional Chinese Medicine,Ningguo 242399,Anhui Province,China)
机构地区:[1]安徽省宁国市中医院药剂科,安徽宁国242399
出 处:《中外医药研究》2023年第8期9-11,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
摘 要:目的:分析药师干预安徽省宁国市中医院Ⅰ类切口预防性使用抗菌药物的临床效果。方法:选取2021年1月—2022年12月安徽省宁国市中医院实施Ⅰ类切口手术治疗患者1088例为研究对象,根据随机数字表法分为观察组和对照组,各544例。对照组采用常规用药干预,观察组采用临床药师干预。比较两组抗菌药物不合理使用情况、不良反应发生率及临床指标。结果:观察组抗菌药物不合理使用率低于对照组,差异有统计学意义(P<0.001);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.001);观察组平均使用抗菌药物时间短于对照组,住院抗菌药物费用、住院费用低于对照组,差异有统计学意义(P<0.001)。结论:药师干预Ⅰ类切口预防性使用抗菌药物具有良好的效果,可以降低抗菌药物不合理使用率及不良反应发生率,缩短使用抗菌药物时间,降低治疗费用。Objective:To analyze the clinical effect of pharmacists'intervention on prophylactic use of antibiotics in ClassⅠincision in Ningguo Hospital of Traditional Chinese Medicine of Anhui Province.Methods:A total of one thousand and eightyeight patients undergoing ClassⅠincision surgery in Ningguo Hospital of Traditional Chinese Medicine of Anhui Province from January 2021 to December 2022 were selected as the study objects,and were divided into observation group and control group according to random number table method,with five hundred and forty-four cases in each group.The control group was treated with routine medication intervention,and the observation group was treated with clinical pharmacists'intervention.The irrational use of antibiotics,incidence of adverse reactions and clinical indexes were compared between the two groups.Results:The irrational utilization rate of antibiotics in the observation group was lower than that in the control group,the difference was statistically significant(P<0.001);The incidence of adverse reactions in observation group was lower than that in control group,and the difference was statistically significant(P<0.001);The average duration of use of antibiotics in the observation group was shorter than that in the control group,and the cost of hospitalization was lower than that in the control group,the difference was statistically significant(P<0.001).Conclusion:Pharmacists'intervention of prophylactic use of antibiotics in ClassⅠincision has good effects,which can reduce the irrational utilization rate of antibiotics and the incidence of adverse reactions,shorten the time of using antibiotics,and reduce the treatment cost.
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